Results 211 to 220 of about 60,195 (236)
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Durvalumab for the treatment of urothelial carcinoma
Drugs of Today, 2017Immunotherapy has revolutionized cancer care in the modern era of oncology. Research in immunotherapy has led to important advances in the treatment of melanoma, non-small cell lung cancer and other malignancies using checkpoint inhibition. Multiple systemic immunotherapies have been approved or are currently being investigated for the management of ...
M, Alsharedi +2 more
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Emerging drugs for urothelial carcinoma
Expert Opinion on Emerging Drugs, 2013Advanced urothelial carcinoma is associated with a poor prognosis. In the metastatic setting, the response rate to first-line, cisplatin-containing chemotherapy is high, but survival is poor. Second-line treatment options are limited. Advanced age at diagnosis and the presence of comorbidities often preclude treatment with cisplatin-containing regimens.
Benjamin A, Gartrell, Guru, Sonpavde
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DNA Methylation in Urothelial Carcinoma
Epigenomics, 2016DNA methylation alterations are common in urothelial carcinoma, a prevalent cancer worldwide caused predominantly by chemical carcinogens. Recent studies have proposed sets of hypermethylated genes as promising diagnostic and prognostic biomarkers from urine or tissue samples, which require validation.
Wolfgang A, Schulz, Wolfgang, Goering
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Erdafitinib to treat urothelial carcinoma
Drugs of Today, 2019Erdafitinib is the first Food and Drug Administration (FDA)-approved oral pan-fibroblast growth factor receptor (FGFR) kinase inhibitor that binds to four FGFRs (FGFR-1 to -4), leading to decreased cell signaling and cellular apoptosis. Erdafitinib also binds to RET, colony-stimulating factor 1 receptor (CSF-1R), platelet-derived growth factor receptor
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Erdafitinib in Urothelial Carcinoma
New England Journal of Medicine, 2019Guru, Sonpavde, Gottfrid, Sjödahl
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Molecular classification and diagnostics of upper urinary tract urothelial carcinoma
Cancer Cell, 2021Yoichi Fujii +2 more
exaly
Comprehensive Genomic Profiling of Upper-tract and Bladder Urothelial Carcinoma
European Urology Focus, 2021Andrea Necchi +2 more
exaly
What Is the Significance of Variant Histology in Urothelial Carcinoma?
European Urology Focus, 2020Shahrokh F Shariat +2 more
exaly