Results 111 to 120 of about 32,745 (219)

The RNA‐ and DNA‐Binding Protein Y‐Box Binding Protein 1 (YB‐1) Regulates iNKT Cell Development

European Journal of Immunology, Volume 56, Issue 5, May 2026.
YB‐1 is essential for invariant NKT cell development, integrating TCR, co‐stimulatory, and IL‐15 signaling to control maturation, subset differentiation, and survival. Its loss at the double‐positive thymocyte stage causes ∼80% iNKT cell depletion, maturation arrest, impaired cytokine production, and increased apoptosis.
Silvia Schulze, Laura Knop, Nouria Jantz‐Naeem, Vladyslava Dovhan, Stephan Fricke, Sascha Kahlfuß, Thomas Schüler, Ursula Bommhardt   +7 more
wiley   +1 more source

Climate and Landscape Controls on Dissolved Organic Matter in Wetland‐Dominated Catchments of the Boreal Plains, Canada

Hydrological Processes, Volume 40, Issue 5, May 2026.
In the subhumid, wetland‐rich, geologically heterogeneous Boreal Plains region of Canada, we found several controls on stream DOC concentration ([DOC]) and DOM composition: An increase in [DOC] and aromaticity as temperature increases throughout the summer, with temperature trend prevailing over the influence of discharge.
Julia Orlova, Kevin J. Devito, Suzanne E. Tank, David Olefeldt   +3 more
wiley   +1 more source

The Contribution to the Assignment of Defined Daily Dose (DDD) to Antineoplastic Drugs of the Italian Working Group on DDD

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 5, May 2026.
ABSTRACT Purpose To report the experience of the Italian Working Group on DDD (Ita‐DDD‐wg) in assigning DDDs to a list of antineoplastic agents. Methods Active substances from the ATC L01 group with no assigned DDD and reimbursed at least once during 2021 by the Italian Healthcare Service were identified.
Angela Boccia, Giulia Hyeraci, Anna Girardi, Rosa Gini, Gianluca Trifirò, Ylenia Ingrasciotta, Andrea Spini, Valentina Ientile, Elisabetta Poluzzi, Giampiero Mazzaglia, Ippazio Cosimo Antonazzo, Casula Manuela, Elena Tragni, Olivia Leoni, Arianna Mazzone, Michele Ercolanoni, Martina Zanforlini, Ursula Kirchmayer, Belleudi Valeria, Marco Finocchietti, Francesco Barone‐Adesi, Giuseppe Roberto   +21 more
wiley   +1 more source

Plasticity in plant hydraulic traits: An evaluation of a common‐taxa experiment across a climatic gradient in the Western U.S.

PLANTS, PEOPLE, PLANET, Volume 8, Issue 3, Page 892-906, May 2026.
Due to climate change, plants are experiencing both prolonged drought events and increasingly variable water availability, prompting the need for better understanding of potential impacts on plant performance, as well as the identification of low‐water‐use plants.
Amelia Keyser‐Gibson, Lloyd Nackley, Youping Sun, Jared Sisneroz, Darren Haver, Ryan Contreras, Ursula K. Schuch, Lorence Oki, Soo‐Hyung Kim   +8 more
wiley   +1 more source

Determining Diffusion Coefficients in Polymer Electrolyte Membranes With Lab Based Micro X‐Ray Fluorescence Analysis: A Proof of Concept

X-Ray Spectrometry, Volume 55, Issue 3, Page 465-472, May/June 2026.
ABSTRACT The diffusion of metal ions in polymer electrolyte membranes is an important parameter for aging and capacity loss in electrochemical cells. Here, the diffusion coefficients of vanadium ions in Nafion membranes are studied. These are important to describe transportation of the ions through the membrane separator in vanadium redox flow ...
Frithjof Mähler, Sven Hampel, Ursula E. A. Fittschen   +2 more
wiley   +1 more source

STAT4基因rs10181656位点的多态性与不明原因复发性自然流产的相关性

Zhongshan Daxue xuebao. Yixue kexue ban, 2017
【目的】探讨信号转导与转录激活因子4（STAT4）基因在不明原因复发性自然流产（URSA）表达及其表达量与 rs10181656位点多态性的关系。【方法】分别采用聚合酶链反应-限制性片段长度多态性法检测332名URSA患者和260名健 康对照者rs10181656位点的基因型频率；应用免疫组织化学技术检测其中的86名URSA患者及77名健康对照者蜕膜STAT4 基因的蛋白表达量。【结果】rs10181656C/G：URSA组中C/C、C/G及G/G基因型频率分别是36.45％、46.99％及16 ...
李银广, 赖嘉杰, 何善阳, 游泽山   +3 more
doaj  

Fluid/function correlation using AI‐based quantification versus central subfield thickness in treatment‐naïve and pre‐treated patients with neovascular AMD in a real‐world setting

Acta Ophthalmologica, Volume 104, Issue 3, Page 305-313, May 2026.
Abstract Purpose To investigate the association between best‐corrected visual acuity (BCVA) and quantitative macular fluid volumes, compared to central subfield thickness (CST) in treatment‐naïve and previously treated patients with active neovascular age‐related macular degeneration (nAMD).
Anna Eidenberger, Gregor S. Reiter, Virginia Mares, Sophie Frank‐Publig, Philipp Fuchs, Magdalena Baratsits, Markus Gumpinger, Georg Faustmann, Alexandra Miere, Catherine Creuzot‐Garcher, Ulrike Scheschy, Laurent Kodjikian, Vincent Gualino, Benjamin Wolff, Stefan Sacu, Ursula Schmidt‐Erfurth   +15 more
wiley   +1 more source

URSA 患者外周血免疫细胞特征及其意义的临床研究

Zhongshan Daxue xuebao. Yixue kexue ban, 2010
【目的】 探讨不明原因复发性流产(URSA)患者处于难免流产和流产后非孕状态等不同临床情况时外周血免疫细胞特征及其临床意义65377; 【方法】 回顾性分析2008-2010年于我院诊疗的自然流产患者184例,就诊时为早期妊娠难免流产的URSA患者55例(URSA难免流产组),同期早期妊娠难免流产的偶发流产患者(sporadic abortion, SA) 23例,作为对照(SA难免流产组)65377;此外,就诊时为未孕状态,距最后一次流产3个月以上URSA患者62例(URSA非孕组),同期未孕状态 ...
doaj  

Safety of beta‐nicotinamide mononucleotide (β‐NMN) pursuant the regulation (EU) 2015/2283 and the bioavailability of nicotinamide from this source in the context of Directive 2002/46/EC

EFSA Journal, Volume 24, Issue 5, May 2026.
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on beta‐nicotinamide mononucleotide (β‐NMN) as a novel food (NF) pursuant to Regulation (EU) 2015/2283, including an evaluation of the safety of its use in food supplements as a source of niacin ...
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan De Henauw, Ángeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Margarita Aguilera‐Gómez, Francesco Cubadda, Thomas Frenzel, Ursula Gundert‐Remy, Francesca Marcon, Harry J. McArdle, Monika Neuhäuser‐Berthold, Miguel Prieto Maradona, Alexandros Siskos, Matthew Wright, Elisa Beneventi, Annamaria Rossi, Maura Magani, Karen Ildico Hirsch‐Ernst   +28 more
wiley   +1 more source

Safety of acute exposure to the food additive glycerol (E 422) from beverages

EFSA Journal, Volume 24, Issue 5, May 2026.
Abstract The European Commission requested EFSA to assess the acute exposure to glycerol (E 422) from slush ice drinks and de‐alcoholised wine. The acute exposure assessment was conducted on a single‑consumption‑event basis considering the reported use levels and analytical data of glycerol in slush ice drinks and the proposed maximum level of 50,000 ...
EFSA Panel on Food Additives and Flavourings (FAF), Laurence Castle, Monica Andreassen, Gabriele Aquilina, Maria Lourdes Bastos, Polly Boon, Biagio Fallico, Reginald FitzGerald, Maria Jose Frutos Fernandez, Bettina Grasl‐Kraupp, Ursula Gundert‐Remy, Rainer Gürtler, Eric Houdeau, Marcin Kurek, Henriqueta Louro, Patricia Morales, Sabina Passamonti, Dominique Turk, Matthew Wright, Consuelo Civitella, Petra Gergelova, Alessandra Tosato, Ana Maria Rincon   +22 more
wiley   +1 more source