Clinical effect of lymphocyte immunotherapy on patients with unexplained recurrent spontaneous abortion [PDF]
Introduction Lymphocyte immunotherapy (LIT) is believed to be a viable treatment for unexplained recurrent spontaneous abortion (URSA), but its effect remains controversial.
Sudong Liu, Xiaodong Gu, Ruiqiang Weng
doaj +6 more sources
Association of thyroid peroxidase antibodies with the rate of first-trimester miscarriage in euthyroid women with unexplained recurrent spontaneous abortion [PDF]
BackgroundUnexplained recurrent spontaneous abortion is a serious reproductive problem of unknown etiology. Thyroid peroxidase antibodies (TPO-Ab) may be associated with pregnancy outcomes in unexplained recurrent spontaneous abortion with normal thyroid
Meilan Liu +12 more
doaj +4 more sources
A missense variant in NCF1 is associated with susceptibility to unexplained recurrent spontaneous abortion [PDF]
Unexplained recurrent spontaneous abortion (URSA) is a major concern in reproductive medicine. Neutrophil cytosolic factor 1 (NCF1) polymorphisms leading to low production of reactive oxygen species (ROS) are strongly associated with autoimmune diseases.
Du Mengxuan +9 more
doaj +4 more sources
KLF4 regulates trophoblast function and associates with unexplained recurrent spontaneous abortion [PDF]
Background Recurrent spontaneous abortionĀ (RSA) is defined as two or more consecutive spontaneous abortions before 20 weeks with the same spouse [1].
Yiling Tan +7 more
doaj +4 more sources
Elevated Homocysteine Levels and Endothelial Dysfunction in Unexplained Recurrent Spontaneous Abortion [PDF]
Lin Qi,1,2,* Yong Yang,1,* Xiaofang Xie,1 Liping Xiang,3 Shuyun Zhang,3 Xue Li,3 Ling Zhou,3 Dan Zhao,1 Ningzheng Dong,2,4,5 Haifang Zhang,1 Hong Zhang3 1Department of Clinical Laboratory, the second Affiliated Hospital of Soochow University ...
Qi L +10 more
doaj +4 more sources
AMPK-mTOR pathway modulates glycolysis reprogramming in unexplained recurrent spontaneous abortion [PDF]
Background Recurrent spontaneous abortion (RSA), whose underlying cause has yet to be fully elucidated, is often classified as unexplained recurrent spontaneous abortion (URSA).
Yihong Chen +5 more
doaj +4 more sources
Association of liver enzyme abnormalities and tobacco exposure with unexplained recurrent spontaneous abortion risk: A caseācontrol study [PDF]
Objective Unexplained recurrent spontaneous abortion is a multifactorial condition with an unclear etiology. This study aimed to investigate the relationship between liver function biomarkers and unexplained recurrent spontaneous abortion and explore ...
Xiaolei Xue +5 more
doaj +2 more sources
Lymphocyte active immunotherapy for unexplained recurrent spontaneous abortion
This study is to evaluate the curative effect of lymphocyte active immune treatment for unexplained recurrent spontaneous abortion. Fourteen randomized controlled trials of 994 subjects were included.
Xian Jiang Wei, Xiao Qin Fang, Ling Tong
doaj +2 more sources
Temporal changes in cyclinD-CDK4/CDK6 and cyclinE-CDK2 pathways: implications for the mechanism of deficient decidualization in an immune-based mouse model of unexplained recurrent spontaneous abortion [PDF]
Background Deficient endometrial decidualization has been associated with URSA. However, the underlying mechanism is poorly understood. This study aimed to investigate the temporal cytokine changes and the involvement of CyclinD-CDK4/6 and CyclinE-CDK2 ...
Zhuo Chang +13 more
doaj +2 more sources
The ESR1 gene in unexplained recurrent spontaneous abortion [PDF]
Recurrent spontaneous abortion (RSA) is a health problem that affects nearly 1% of fertile couples. However, the underlying etiology and mechanism(s) remain elusive. The aim of this study was to investigate estrogen receptor (ESR) 1 gene polymorphisms for risk association of unexplained recurrent spontaneous abortion (URSA) in the Chinese Han ...
Hong Pan, Binbin Wang, Sirui Zhou
exaly +3 more sources

