Results 41 to 50 of about 7,670 (198)

IFN-γ VERSUS IL-10 IN SITU EXPRESSION IN RECURRENT SPONTANEOUS ABORTION

The Iraqi Journal of Medical Sciences, 2009
Background: The possible immunological bases of recurrent spontaneous abortion (RSA) are still largely unknown, aberrant type 1 cytokine production; interferon-γ (IFNγ), and a defective type 2 cytokine; Interleukin-10 (IL-10) has been suggested to be ...
Asmaa’ Baqer Al-Obaidi , Manal Adnan Habib   +1 more
doaj   +1 more source

Association between -238 but not -308 polymorphism of Tumor necrosis factor alpha (TNF-alpha)v and unexplained recurrent spontaneous abortion (URSA) in Chinese population [PDF]

, 2010
Objectives TNF-alpha is a critical cytokine produced by Th1 cells while altered T helper 1 (Th1)-Th2 balance is found crucial for a successful pregnancy.
Chunmei Liu, Jing Wang, Sirui Zhou, Binbin Wang, Xu Ma   +4 more
core   +1 more source

Sperm DNA fragmentation, recurrent implantation failure and recurrent miscarriage [PDF]

, 2015
Evidence is increasing that the integrity of sperm DNA may also be related to implantation failure and recurrent miscarriage (RM). To investigate this, the sperm DNA fragmentation in partners of 35 women with recurrent implantation failure (RIF ...
Aitken, AllanA Pacey, Barratt, Bellver, Berry, Bhattacharya, Bricker, Bronet, Bungum, Carol Coughlan, Carrell, Cutting, Daya, Duran, Evenson, Evenson, Fernández, Gil-Villa, Gnoth, Helen Clarke, Jane Saxton, Mitchell, Morris, Pacey, Pacey, Practice, Rachel Cutting, Ribas-Maynou, Robinson, Sarah Waite, Sharma, Simon, Spanò, Stewart, Stirrat, Thonneau, Tinchiu Li, Tomlinson, William Ledger, Zini, Zini, Zini, Zini   +42 more
core   +3 more sources

Methylenetetrahydrofolate reductase and transcobalamin genetic polymorphisms in human spontaneous abortion: biological and clinical implications [PDF]

, 2004
The pathogenesis of human spontaneous abortion involves a complex interaction of several genetic and environmental factors. The firm association between increased homocysteine concentration and neural tube defects (NTD) has led to the hypothesis that ...
Henrik Zetterberg
core   +1 more source

The alteration and potential relationship of vaginal microbiota and chemokines for unexplained recurrent spontaneous abortion. [PDF]

Medicine (Baltimore), 2020
Abstract The diagnosis and treatment of unexplained recurrent spontaneous abortion (URSA) is an important and hot topic in the field of obstetrics and gynecology. During our clinical investigation (observation), we have found that URSA patients usually experience recurrent vaginitis or vaginal dysbacteriosis during periods of ...
Fan T, Zhong XM, Wei XC, Miao ZL, Luo SY, Cheng H, Xiao Q.   +6 more
europepmc   +3 more sources

Analysis of copy number variations and possible candidate genes in spontaneous abortion by copy number variation sequencing

Frontiers in Endocrinology, 2023
IntroductionEmbryonic chromosomal abnormalities represent a major causative factor in early pregnancy loss, highlighting the importance of understanding their role in spontaneous abortion.
Wei Bai, Qi Zhang, Zhi Lin, Jin Ye, Xiaoqi Shen, Linshuang Zhou, Wenpin Cai   +6 more
doaj   +1 more source

Study on the immunomodulatory mechanism of vitamin D in patients with unexplained recurrent spontaneous abortion. [PDF]

Heliyon
To investigate the mechanism of vitamin D level on the regulation of peripheral blood lymphocyte subsets and serum Th1/Th2 cytokines in patients with unexplained recurrent spontaneous abortion (URSA).Eighty female patients with URSA attending Sichuan Jinxin Xinan Women's and Children's Hospital from January 2020 to May 2021 were selected as the study ...
Yang P, Lu F.
europepmc   +4 more sources

Serum relaxin levels are reduced in pregnant women with a history of recurrent miscarriage, and correlate with maternal uterine artery Doppler indices in first trimester [PDF]

, 2009
Objectives: Defective implantation is a mechanism for recurrent pregnancy loss (RPL). We sought to determine whether the serum expression of human relaxin-2 (RLX) is impaired in women with a history of RPL.
Bogic, Bogic, Carp, Craig, Dilly O.C. Anumba, Emmer, Gardosi, Goldsmith, Hollis, Jauniaux, Jivraj, Johnson, Johnson, Laird, MacLennan, Maynard, Mtiraoui, Nicolaides, Palomba, Parry, Petersen, Piccinni, Prakash, Saad El Gelany, Sakbun, Salim, Sarah L. Elliott, Seki, Tin C. Li, Unemori, Yki-Jarvinen   +30 more
core   +2 more sources

Expression of GRIM-19 in unexplained recurrent spontaneous abortion and possible pathogenesis [PDF]

MHR: Basic science of reproductive medicine, 2018
Is aberrant expression of gene associated with retinoid-interferon-induced mortality-19 (GRIM-19) associated with unexplained recurrent spontaneous abortion (URSA)?GRIM-19 deficiency may regulate regulatory T cell/T helper 17 cell (Treg/Th17) balance partly through reactive oxygen species (ROS)-mammalian target of rapamycin (mTOR) signaling axis in ...
Yang Yang, Laiyang Cheng, Xiaohui Deng, Hongling Yu, Lan Chao   +4 more
openaire   +2 more sources

Plasma homocysteine and vitamin B12 serum levels, red blood cell folate concentrations, C677T methylenetetrahydrofolate reductase gene mutation and risk of recurrent miscarriage: a case-control study in Spain. [PDF]

, 2014
Background: Hyperhomocysteinemia and methylenetetrahydrofolate reductase (MTHFR) gene mutation have been postulated as a possible cause of recurrent miscarriage (RM).
Balasch Cortina, Juan, Carmona Herrera, Francisco, Creus Ferré, Montserrat, Deulofeu i Piquet, Ramon, Peñarrubia, Joanna   +4 more
core   +2 more sources