Results 81 to 90 of about 32,745 (219)

Epileptic–Dyskinetic Encephalopathy Associated with a PPP3CA Variant: Expansion of the Phenotypic Spectrum

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Bruno Antunes Contrucci   +10 more
wiley   +1 more source

Differential segment‐specific signalling pathways for guanylate cyclase C‐activated anion secretion in murine ileocolon

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Guanylate cyclase‐C (GC‐C) is the receptor for endogenous (uro)guanylin peptides, bacterial toxins and pharmacological analogues. Receptor activation leads to intestinal fluid loss, but also activates an antiproliferative pathway and is a promising target in colorectal cancer therapy.
Renjie Xiu   +4 more
wiley   +1 more source

Translocation effects on regional and local population viability and connectivity

open access: yesConservation Biology, EarlyView.
Abstract Translocations and reintroductions aim to improve the viability of isolated populations and promote connectivity for large carnivores. However, there is no established framework for assessing their success. We used the Eurasian lynx (Lynx lynx) in western and central Europe to assess the impact of translocations on the viability of six ...
Eva Sánchez Arribas   +25 more
wiley   +1 more source

Data-Driven Techniques for Detecting Dynamical State Changes in Noisily Measured 3D Single-Molecule Trajectories

open access: yesMolecules, 2014
Optical microscopes and nanoscale probes (AFM, optical tweezers, etc.) afford researchers tools capable of quantitatively exploring how molecules interact with one another in live cells.
Christopher P. Calderon
doaj   +1 more source

Predictive utility of a simple cranial magnetic resonance imaging score at term‐equivalent age for cerebral palsy

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
This study evaluated the Total Abnormality Score (TAS) from cMRI at term‐equivalent age as a predictor of cerebral palsy (CP) in 137 infants born preterm or with low birthweight. Infants who developed CP had significantly higher TAS values (median 11 vs 2), with a TAS cut‐off of 9.5 demonstrating high sensitivity (88.9%) and specificity (91.4%) for CP ...
Anne‐Kathrin Dathe   +6 more
wiley   +1 more source

Experimenting with urban stressors: a network-based approach to systemic resilience through the URSA framework

open access: yesUrban Transformations
Understanding how shocks cascade through interdependent urban systems is essential for designing effective resilience strategies. We introduce the Urban Resilience and Sustainability Alliance (URSA), a network-based framework that represents a city’s ...
Mozhgan PourmoradNasseri   +4 more
doaj   +1 more source

Correction: Calderon, C.P. Data-Driven Techniques for Detecting Dynamical State Changes in Noisily Measured 3D Single-Molecule Trajectories. Molecules 19, 18381-18398

open access: yesMolecules, 2015
The author wishes to make the following corrections to paper [1] (doi:10.3390/molecules191118381, website: http://www.mdpi.com/1420-3049/19/11/18381):
Christopher P. Calderon
doaj   +1 more source

The Ursa Major Supercluster [PDF]

open access: yesSymposium - International Astronomical Union, 1983
The Ursa Major supercluster is an association of ten Abell clusters which lie within 7° of each other. The center of the system has equatorial coordinates RA (1950.0) and galactic coordinates l = 143°, b = 60°.
openaire   +1 more source

Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity

open access: yesObesity Reviews, EarlyView.
ABSTRACT Excess adiposity is not a recently developed problem but has existed since at least the upper Paleolithic, allowing evolutionary selection pressures to adapt the physiology of the pregnant woman and the feto‐placental unit for maternal and fetal protection.
Gernot Desoye   +6 more
wiley   +1 more source

CD4CD25Foxp3 regulatory T cells regulate immune balance in unexplained recurrent spontaneous abortion via the Toll-like receptor 4/nuclear factor-κB pathway

open access: yesJournal of International Medical Research, 2020
Objective The present study aimed to evaluate the effects of cluster of differentiation (CD)4 + CD25 + forkhead box p3 (Foxp3) + regulatory T cells (Tregs) on unexplained recurrent spontaneous abortion (URSA) and the associated mechanisms.
Shuang Qin   +6 more
doaj   +1 more source

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