Brazilian Journal of Pharmaceutical Sciences, 2015 Ursolic acid is a promising candidate for treatment of Chagas disease; however it has low aqueous solubility and intestinal absorption, which are both limiting factors for bioavailability. Among the strategies to enhance the solubility and dissolution of
Josimar Oliveira Eloy +3 more
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Ursolic acid targets secreted phosphoprotein 1 to regulate Th17 cells against metabolic dysfunction-associated steatotic liver disease [PDF]
Clinical and Molecular HepatologyBackground/Aims Metabolic dysfunction-associated steatotic liver disease (MASLD) has become an increasingly important health challenge, with a substantial rise linked to changing lifestyles and global obesity.
Yiyuan Zheng +13 more
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Two New Triterpenes and Other Compounds from (Lamiaceae)
Natural Product Communications, 2017 Two new triterpenoids, maquatic acid ( 1 ), a 2,3- seco -triterpene having an acetal in its A-ring, and 3- O -benzoyltormentic acid ( 2 ), were isolated from underground parts of Mentha aquatica , in addition to twelve known compounds, tormentic acid ( 3
Maria Ferhat +3 more
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PLoS ONE, 2018 BackgroundHyperurecemia is usually associated with gout and various metabolic arthritis disorders. Limited medications are available to manage such conditions.
Eman Abu-Gharbieh +3 more
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The Preparation and Characterization of Inclusion Complex of Ursolic Acid with γ-Cyclodextrin
, 2011 In order to increase the solubility of ursolic acid, the inclusion complexes of ursolic acid with γ-cyclodextrin were prepared by grinding, ultrasonic and stirring methods.
Su Mei Bi, Wei Zong
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Effect of Combined Treatment with Ursolic Acid and Resveratrol on Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate [PDF]
, 2015 In this study, the effects of combining ursolic acid + resveratrol, for possible combined inhibitory effects on skin tumor promotion, were evaluated.
DiGiovanni, John +6 more
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CHEMICAL COMPOSITION AND ANTI-INFLAMMATORY ACTIVITY OF VERBENA SUPINA L ; GROWING IN EGYPT
Zagazig Journal of Pharmaceutical Sciences, 2003 Phytochemical investigation of the chloroform extract of Verbena supina L. afforded ursolic acid, oleanolic acid, 3β, 24-dihydroxy-urs-12-en-28-oic acid and 3 β,24-dihydroxy-olean-12-en-28-oicacid.The ethyl acetate extract yielded the pheny1propanoid ...
Mahmoud Abdel-Aal , Salah Ghareib
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Effects of ursolic acid consumption on strength and body composition
, 2013 Ursolic acid is a pentacyclic triterpene found in a wide variety of commonly consumed fruits and herbs with potential mechanisms for fat loss and skeletal muscle hypertrophy in in-vitro and murine models.
Alex Joseph Mattingly
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Influence of ursolic acid on glucooligosaccharides synthesized by dextransucrase from Leuconostoc mesenteroides Lm 28 [PDF]
Journal of BioScience and Biotechnology, 2015 A study of modulation of the reactions catalyzed by dextransucrase from Leuconostoc mesenteroides Lm 28 strain in the presence of triterpenoid ursolic acid was carried out.
TONKA VASILEVA +3 more
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Group IIA secretory PLA2 inhibition by Ursolic Acid: a potent anti-inflammatory molecule
, 2007 Ursolic acid (3β-hydroxy-urs-12-en-28-oic acid) isolated from many medicinal plants has diverse pharmacologically important properties, including strong anti-inflammatory activity. However its interaction with proinflammatory PLA2 is not known.
Nataraj, A. +3 more
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