Results 81 to 90 of about 2,518,282 (213)

Antibacterial and Synergistic Activity of Pentacyclic Triterpenoids Isolated from Alstonia scholaris

open access: yesMolecules, 2016
(1) Background: Alstonia scholaris (Apocynaceae) is an important medicinal plant that has been historically used in “Dai” ethnopharmacy to treat infectious diseases in China.
Chao-Min Wang   +5 more
doaj   +1 more source

Characterization of functional metabolites in broccoli by‐product using green extraction with supercritical fluids

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 11, Page 6789-6799, 30 August 2026.
Abstract BACKGROUND The present study aimed to valorize broccoli by‐products (leaves and stems) through the extraction of bioactive compounds using supercritical fluid extraction (SFE). The influence of broccoli variety, plant part and maturation stage on total phenolic content (TPC), antioxidant activity and antimicrobial properties was evaluated ...
Iris Gudiño   +5 more
wiley   +1 more source

Effect of ursolic acid from epicuticular waxes of jacaranda decurrens on schizaphis graminum [PDF]

open access: yes, 1992
Ursolic acid from Jacaranda decurrens showed toxicity and feeding deterrency towards the greenbug Schizaphis graminum. Biological activity was determined by analyzing ursolic acid effects on the survival, reproductive index, and population growth rate of
Zúñiga, G. E.   +4 more
core   +1 more source

SYNTHESIS AND CHARACTERIZATION OF NEW IMINE AND PTHALIC ACID DERIVATIVES OF URSOLIC ACID [PDF]

open access: yes, 2014
Objective: The current work envisages synthesis of novel ursolic acid derivatives and characterization by spectral methods that can be possible candidates for anti-inflammatory and anticancer activity.
Babar, Shrikant, Laddha, Kirti
core   +1 more source

Effects of Ursolic Acid on Colorectal Cancer: A Review of Recent Evidence

open access: yesNutraceuticals
Colorectal cancer is the third leading cause of cancer-related deaths, and the five-year survival rate of the metastatic disease is less than 15%. Treatment approaches include surgery, systemic chemotherapy and radiotherapy. The aggressive nature and low
Amanda Kornel, Evangelia Tsiani
doaj   +1 more source

Kinetic Compatibility as a Predictor of PTP1B Inhibitor Combination Outcomes: An Integrated Experimental and Computational Study

open access: yesChemMedChem, Volume 21, Issue 16, 27 August 2026.
Combining PTP1B inhibitors of distinct kinetic mechanisms determines their pharmacological outcome. Integrating enzyme kinetics, docking, molecular dynamics, and membrane‐permeability simulations, we show that mechanistically compatible pairs (competitive + competitive; uncompetitive + mixed) yield additivity, whereas competitive + uncompetitive ...
Jonathan Trapala   +7 more
wiley   +1 more source

PEG–Ursolic Acid Conjugate: Synthesis and In Vitro Release Studies

open access: yes, 2014
A highly water-soluble macromolecular compound of ursolic acid with mono-methoxypoly(ethylene glycol) (mPEG) was prepared. The physicochemical properties and stabilities under different conditions were investigated.
ZACCHIGNA, MARINA   +8 more
core   +1 more source

Pharmacological studies on the laxative effects of Fagonia indica on rodents

open access: yesBangladesh Journal of Pharmacology, 2019
This study explores the pharmacological basis for the folk use of Fagonia indica in constipation using in vivo and in vitro assays. The crude extract of F. indica contained tannins, saponins, anthraquinones, alkaloids, flavonoids, glycosides and phenols.
Muhammad Zeeshan Ali   +3 more
doaj   +1 more source

A phase I pharmacokinetic study of ursolic acid nanoliposomes in healthy volunteers and patients with advanced solid tumors

open access: yes, 2013
Zhongling Zhu,1,4 Zhengzi Qian,2,4 Zhao Yan,1,4 Cuicui Zhao,2,4 Huaqing Wang,2,4 Guoguang Ying3,41Department of Clinical Pharmacology, 2Department of Lymphoma, 3Laboratory of Tumor Cell Biology, Tianjin Medical University Cancer Institute and Hospital ...
Qian Z   +5 more
core  

Ursolic acid reduces the metalloprotease/anti-metalloprotease imbalance in cerebral ischemia and reperfusion injury

open access: yes, 2016
Yanzhe Wang, Zhiyi He, Shumin Deng Department of Neurology, The First Affiliated Hospital of China Medical University, Shenyang, People’s Republic of China Background: Activators of PPARs, particularly PPARγ, may be effective ...
Deng S, He Z, Wang Y
core  

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