Results 111 to 120 of about 20,067 (234)

Secondary metabolites and their exploitation in medicine [PDF]

, 2009
Many of the medicinal products available today are derived from secondary metabolites. Plants remain the main source of such therapeutic agents but other sources are being explored and exploited.
Baldacchino, Alexandra, Grech, Alfred, Tufignio, Marcel   +2 more
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The effects of ursolic acid on cytokine production via the MAPK pathways in leukemic T-cells [PDF]

, 2013
Ursolic acid (UA) is a pentacyclic triterpenoid carboxylic acid that is found in plants and herbal products. It is one of the chemopreventive agents, which can suppress cancer cell proliferation and induce apoptosis.
Brimson, Sirikalaya, Kaewthawee, Narawan
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Ursolic acid attenuates diabetic mesangial cell injury through the up-regulation of autophagy via miRNA-21/PTEN/Akt/mTOR suppression.

PLoS ONE, 2015
ObjectiveTo investigate the effect of ursolic acid on autophagy mediated through the miRNA-21-targeted phosphoinositide 3 kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) pathway in rat mesangial cells cultured under high glucose
Xinxing Lu, Qiuling Fan, Li Xu, Lin Li, Yuan Yue, Yanyan Xu, Yan Su, Dongcheng Zhang, Lining Wang   +8 more
doaj   +1 more source

The potency of ursolic acid as a co-chemotherapy agent for breast cancer: Bibliometric analysis and bioinformatic study

Notulae Scientia Biologicae
Ursolic acid, a triterpenoid compound found in various plants, has been garnered significant attention as potential co-chemotherapeutic agent for breast cancer therapy.
Farras A. RAHMAN, Rohmad Y. UTOMO, Muthi’ IKAWATI   +2 more
doaj   +1 more source

Comparative proteomics—network analysis of proteins responsible for ursolic acid–induced cytotoxicity in colorectal cancer cells

Tumor Biology, 2017
Ursolic acid is a key active compound present in many medicinal herbs that have been widely used in traditional Chinese medicine for the clinical treatment of various cancers.
Qiaoyan Cai, Jing Lin, Ling Zhang, Jiumao Lin, Lili Wang, Daxin Chen, Jun Peng   +6 more
doaj   +1 more source

Immortelle (Xeranthemum annum L.) as a natural source of biologically active substances [PDF]

, 2011
Antioxidant and antimicrobial effects, total phenolic content and flavonoid concentrations of methanolic, acetone and ethyl acetate extracts from Xeranthemum annuum L. were investigated in this study.
Branković, Snežana R., Radojević, Ivana D., Stanković, Milan S., Stefanović, Olgica D., Topuzović, Marina D., Čomić, Ljiljana R.   +5 more
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Ursolic acid fromHippophae rhamnoides [PDF]

Chemistry of Natural Compounds, 1979
É. N. Novruzov, S. M. Aslanov, A. A. Imanova, Z. I. Gasanova   +3 more
openaire   +1 more source

Analysis of phytoconstituent profile of fenugreek - Trigonella foenum-graecum L. - seed extracts [PDF]

, 2018
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Cziáky, Zoltán, Gálné Remenyik, Judit, Moş, Liana, Máthé, Endre, Pribac, Ciprian, Sinka, László Tamás, Turcuş, Violeta, Vigh, Szabolcs   +7 more
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Leonurus cardiaca L. herb - a derived extract and an ursolic acid as the factors affecting the adhesion capacity of Staphylococcus aureus in the context of infective endocarditis [PDF]

, 2014
The objective was an assessment of the impact of Leonurus cardiaca L. extract (LCE) and ursolic acid (UA) on the adhesive properties of Staphylococus aureus NCTC 8325 strain, expressing virulence factors important in the pathogenesis of infective ...
Micota, Bartłomiej, Podsędek, Anna, Redzynia, Małgorzata, Różalska, Barbara, Sadowska, Beata   +4 more
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Ursolic acid inSorbus aucuparia [PDF]

Chemistry of Natural Compounds, 1969
A. G. Shavva, L. G. Matyukhina, I. A. Saltykova   +2 more
openaire   +1 more source