Results 81 to 90 of about 20,067 (234)

Oxidation and Acetylation of Ursolic and Oleanolic Acids Isolated from Fragraea fragrans fruits; Antiproliferation of P388 Leukemia Cells

Indonesian Journal of Chemistry, 2014
An interesting natural product chemistry aspect of Fragraea fragrans is that their fruits are richness with ursolic acid and its isomer oleanolic acid (3.05% of dried powder).
Dasril Basir, Julinar Julinar, Eva Agustriana, Budi Untari   +3 more
doaj   +1 more source

Loganin, an Iridoid Glycoside, Alleviates Paclitaxel‐Induced Skeletal Muscle Toxicity by Enhancing Mitochondrial Function, Boosting Antioxidant Defenses, and Reducing Cellular Senescence

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 4, April 2026.
ABSTRACT Mitochondrial dysfunction and energy imbalance caused by chemotherapy are key contributors to skeletal muscle atrophy, which severely impacts the quality of life in cancer patients. Paclitaxel, a commonly used chemotherapeutic agent, is known to promote muscle wasting and cellular senescence, largely by impairing mitochondrial function.
Yu‐Fan Chuang, Cai‐Rong Wu, Wan‐Hsuan Chang, Ying‐Jung Su, Hung‐Te Hsu, Fan‐Li Lin, Yi‐Ching Lo   +6 more
wiley   +1 more source

Inhibitory effects of ursolic acid from Bushen Yijing Formula on TGF-β1-induced human umbilical vein endothelial cell fibrosis via AKT/mTOR signaling and Snail gene

Journal of Pharmacological Sciences, 2019
The present study aimed to investigate the functional components from Bushen Yijing Formula and their inhibition of endothelial–mesenchymal transition (EndMT) and fibrosis in human umbilical vascular endothelial cells (HUVECs). HUVEC fibrosis was induced
Ke Zhu, Cuixiang Cao, Jiaqi Huang, Zixuan Cheng, Donghai Li, Xiuting Liu, Yueping Mao, Qing Qi   +7 more
doaj   +1 more source

Chemical Constituents of Vitex ovata (Verbenaceae) [PDF]

, 1997
Three compounds, luteolin, ursolic acid and meta-hydroxybenzoic acid were isolated from the leaves of Vitex ovata.
Aimi, Norio, Hamzah, Ahmad Sazali, Lajis, Md Nordin, Ramli, Irmawati   +3 more
core  

The potential of Ganoderma lucidum extracts as bioactive ingredients in topical formulations, beyond its nutritional benefits [PDF]

, 2017
Ganoderma lucidum was characterized in terms of nutritional value and chemical composition. Thereafter, ethanolic Soxhlet extracts were evaluated for antioxidant, anti-inflammatory, antityrosinase, antimicrobial and cytotoxic effects, and further ...
Alves, Maria José, Barreiro, M.F., Barros, Lillian, Calhelha, Ricardo C., Ferreira, Isabel C.F.R., González-Paramás, Ana María, Heleno, Sandrina A., Taofiq, Oludemi   +7 more
core   +1 more source

Pharmacological studies on the laxative effects of Fagonia indica on rodents

Bangladesh Journal of Pharmacology, 2019
This study explores the pharmacological basis for the folk use of Fagonia indica in constipation using in vivo and in vitro assays. The crude extract of F. indica contained tannins, saponins, anthraquinones, alkaloids, flavonoids, glycosides and phenols.
Muhammad Zeeshan Ali, Malik Hassan Mehmood, Muhammad Saleem, Anwar-ul-Hassan Gilani   +3 more
doaj   +1 more source

Antimicrobial Effect of Spices and Their Phytochemicals: A Novel Approach to Overcoming Antibiotic Resistance

MedComm, Volume 7, Issue 4, April 2026.
This graphical abstract shows the antibacterial potential of phytochemicals from 15 spices, showcasing key compounds, their extraction methods, and mechanisms of action. It highlights membrane disruption, ROS generation, enzyme inhibition, and biofilm prevention as core antibacterial pathways.
Hettiyahandi Binodh De Silva, Yanqi Dai, Shervanthi Homer‐Vanniasinkam, Mohan Edirisinghe   +3 more
wiley   +1 more source

Inhibitory activity of Kaki calyx extracts and their triterpene compounds on recombinant hepatitis C virus NS3/4A protease [PDF]

, 2018
柿蔕のヘキサン、メタノール、50 % アセトン抽出物の、組み替えhepatitis C virus (HCV)の NS3/4A 蛋白質分解酵素に対する阻害活性を検討した。50 % アセトン抽出物が最も阻害活性が強く、この抽出物をSephadex LH20カラムで分画を行なった。得た各画分のうち阻害活性の強かった70 %メタノール画分を、さらにシリカゲルカラム／薄層クロマトグラフィーで分画し、トリテルペンのベルリン酸、オレアノール酸、ウルソール酸を分離した。これらのトリテルペンはpolycyclic ...
Isao OHTSUKA, Kazuki TSUCHIYA, Nobuko KAKIUCHI, Tairiku KUROIWA, Toshiyuki ATSUMI, あつみ としゆき, おおつか いさお, かきうち のぶこ, くろいわ たいりく, つちや かずき, 土谷 和紀, 垣内 信子, 大塚 功, 渥美 聡孝, 黒岩 大陸   +14 more
core   +1 more source

Targeting Ferroptosis With Natural Products for the Treatment of Skeletal System Disease: An Updated Review

Journal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.
ABSTRACT Skeletal system diseases, encompassing chronic disorders of the skeletal system which commonly include osteoarthritis, rheumatoid arthritis, osteoporosis and osteosarcoma. Their incidence rates have been increasing in recent years, resulting in significant social and economic burdens.
Qian Yi, Jinye Li, Guotian Luo, Jiachen Li, Dahang Yang, Wei Sun, Weichao Sun, Wei You, Lei Yang   +8 more
wiley   +1 more source

Antibacterial and Synergistic Activity of Pentacyclic Triterpenoids Isolated from Alstonia scholaris

Molecules, 2016
(1) Background: Alstonia scholaris (Apocynaceae) is an important medicinal plant that has been historically used in “Dai” ethnopharmacy to treat infectious diseases in China.
Chao-Min Wang, Hsiao-Ting Chen, Zong-Yen Wu, Yun-Lian Jhan, Ching-Lin Shyu, Chang-Hung Chou   +5 more
doaj   +1 more source