Results 201 to 210 of about 50,217 (224)

Bruton's Tyrosine Kinase Inhibitors: Mechanisms, Efficacy, Toxicities and Applications for the Treatment of Human Diseases

open access: yesMedComm, Volume 7, Issue 10, October 2026.
BTK inhibitors suppress malignant B‐cell signaling while simultaneously reshaping immune regulation through effects on T cells and the tumor microenvironment. These mechanisms support combination immunotherapy strategies and also underlie the expanding application of BTK inhibitors in solid tumors, autoimmune and inflammatory diseases.
Miao Sun, Dengju Li, Jia Wei
wiley   +1 more source

Airway Risk in Angioedema: Validation of a Clinical Triage Algorithm for ENT Referral

open access: yesOtolaryngology–Head and Neck Surgery, Volume 175, Issue 4, Page 874-880, October 2026.
Abstract Objective To identify clinical factors associated with laryngeal involvement in patients with angioedema and to validate a triage algorithm for determining the need for nasopharyngoscopic evaluation in the emergency department (ED). Study Design A retrospective review was performed of all patients presenting to the ED with angioedema or ...
Dan Yaniv   +7 more
wiley   +1 more source

Population Pharmacokinetics of Topical Timolol Maleate Gel in Healthy Volunteers and Infants With Superficial Infantile Hemangioma

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 10, October 2026.
ABSTRACT Although timolol ophthalmic solutions or hospital‐compounded formulations have been used off‐label for the treatment of superficial infantile hemangioma (IH), no topical timolol formulation has been developed specifically for this indication.
Li Li   +9 more
wiley   +1 more source

Dermographism in chronic spontaneous urticaria: associations with disease activity, autoimmunity, and disease duration. [PDF]

open access: yesFront Immunol
Trajkova V   +7 more
europepmc   +1 more source

Rebound Pruritus and Urticaria After Discontinuation of Chronic Antihistamine Use—A Scoping Review

open access: yesClinical &Experimental Allergy, Volume 56, Issue 10, Page 1205-1214, October 2026.
Rebound pruritus and urticaria have been reported after discontinuation of chronic cetirizine or levocetirizine use only. Symptoms typically occur within 0.5–5 days after stopping therapy and appear more frequently reported in female patients. Re‐initiation of antihistamines is the most commonly effective management strategy, highlighting the need for ...
Jun Jie Benjamin Seng   +2 more
wiley   +1 more source

Emerging Paediatric Uses of Dupilumab Beyond Approvals

open access: yesClinical &Experimental Allergy, Volume 56, Issue 10, Page 1162-1176, October 2026.
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese   +11 more
wiley   +1 more source

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