BTK inhibitors suppress malignant B‐cell signaling while simultaneously reshaping immune regulation through effects on T cells and the tumor microenvironment. These mechanisms support combination immunotherapy strategies and also underlie the expanding application of BTK inhibitors in solid tumors, autoimmune and inflammatory diseases.
Miao Sun, Dengju Li, Jia Wei
wiley +1 more source
Risk of Abnormal Uterine Bleeding in Women with Chronic Spontaneous Urticaria: Korean Nationwide Population-Based Cohort. [PDF]
Park SY, Kim JY, Song JE.
europepmc +1 more source
Airway Risk in Angioedema: Validation of a Clinical Triage Algorithm for ENT Referral
Abstract Objective To identify clinical factors associated with laryngeal involvement in patients with angioedema and to validate a triage algorithm for determining the need for nasopharyngoscopic evaluation in the emergency department (ED). Study Design A retrospective review was performed of all patients presenting to the ED with angioedema or ...
Dan Yaniv +7 more
wiley +1 more source
Clinical and Immunological Associations of Plasma Platelet-Activating Factor in Chronic Spontaneous Urticaria. [PDF]
Lapiņa L +3 more
europepmc +1 more source
ABSTRACT Although timolol ophthalmic solutions or hospital‐compounded formulations have been used off‐label for the treatment of superficial infantile hemangioma (IH), no topical timolol formulation has been developed specifically for this indication.
Li Li +9 more
wiley +1 more source
Dermographism in chronic spontaneous urticaria: associations with disease activity, autoimmunity, and disease duration. [PDF]
Trajkova V +7 more
europepmc +1 more source
Investigation of factors influencing intravenous glucocorticoid treatment course in severe acute urticaria: A retrospective study. [PDF]
Wang K +5 more
europepmc +1 more source
Rebound Pruritus and Urticaria After Discontinuation of Chronic Antihistamine Use—A Scoping Review
Rebound pruritus and urticaria have been reported after discontinuation of chronic cetirizine or levocetirizine use only. Symptoms typically occur within 0.5–5 days after stopping therapy and appear more frequently reported in female patients. Re‐initiation of antihistamines is the most commonly effective management strategy, highlighting the need for ...
Jun Jie Benjamin Seng +2 more
wiley +1 more source
Immediate Fluoxetine Hypersensitivity With Predominant Airway and Oropharyngeal Symptoms in an Adolescent. [PDF]
Viegas M +4 more
europepmc +1 more source
Emerging Paediatric Uses of Dupilumab Beyond Approvals
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese +11 more
wiley +1 more source

