Results 231 to 240 of about 81,528 (247)

Autoimmune chronic spontaneous urticaria.

Journal of Allergy and Clinical Immunology, 2022
Chronic spontaneous urticaria (CSU) is a debilitating mast cell-driven disease characterized by recurrent wheals and/or angioedema. Substantial progress has been made in dissecting the 2 main autoimmune mechanisms that drive the pathogenesis of CSU. Type
P. Kolkhir, M. Muñoz, R. Asero, M. Ferrer, E. Kocatürk, M. Metz, Y. Xiang, M. Maurer   +7 more
semanticscholar   +1 more source

Anti‐KIT antibody, barzolvolimab, reduces skin mast cells and disease activity in chronic inducible urticaria

Allergy. European Journal of Allergy and Clinical Immunology, 2022
Chronic inducible urticaria (CIndU) is characterized by mast cell (MC)‐mediated wheals in response to triggers: cold in cold urticaria (ColdU) and friction in symptomatic dermographism (SD).
D. Terhorst‐Molawi, T. Hawro, E. Grekowitz, L. Kiefer, Kunal Merchant, Diego Alvarado, L. Thomas, T. Hawthorne, E. Crowley, M. Heath-Chiozzi, M. Metz, M. Maurer   +11 more
semanticscholar   +1 more source

Biologics for the Use in Chronic Spontaneous Urticaria: When and Which.

Journal of Allergy and Clinical Immunology: In Practice, 2021
Guidelines for the treatment of chronic spontaneous urticaria (CSU) recommend the use of the IgE-targeted biologic omalizumab in patients with antihistamine-refractory disease.
M. Maurer, D. Khan, Daniel Elieh-Ali-Komi, A. Kaplan   +3 more
semanticscholar   +1 more source

Jingfang Granules improve glucose metabolism disturbance and inflammation in mice with urticaria by up-regulating LKB1/AMPK/SIRT1 axis.

Journal of Ethnopharmacology, 2022
ETHNOPHARMACOLOGICAL RELEVANCE Jingfang Granule (JFG) is a classical traditional Chinese medicine prescription to empirically treat skin disease such as urticaria in clinical practice.
Chenghong Sun, Hongbao Liang, Yun-hao Zhao, Shirong Li, Xiangzi Li, Xi Yuan, Guoliang Cheng, Yongkang Zhang, Mingfei Liu, Yongxia Guan, Jing-chun Yao, Guimin Zhang   +11 more
semanticscholar   +1 more source

Chronic spontaneous urticaria guidelines: What is new?

Journal of Allergy and Clinical Immunology, 2022
Urticaria is a heterogeneous inflammatory disorder that can be acute or chronic and is defined by the appearance of wheals, angioedema, or both. Very recently, the newest update and revision of the international European Academy of Allergy and Clinical ...
T. Zuberbier, J. Bernstein, M. Maurer
semanticscholar   +1 more source

Chronic Spontaneous Urticaria: A Review.

Journal of the American Medical Association (JAMA)
Importance Chronic spontaneous urticaria affects approximately 1% of the general population worldwide, including approximately 3 million people in the US, impairs patients' quality of life, and is associated with multiple comorbidities.
P. Kolkhir, H. Bonnekoh, M. Metz, Marcus Maurer   +3 more
semanticscholar   +1 more source

The role of eosinophils in chronic spontaneous urticaria.

Journal of Allergy and Clinical Immunology, 2020
Chronic spontaneous urticaria (CSU) is considered to be primarily a mast cell-driven disease. However, recent evidence suggests that eosinophils may also have an axial role in symptomology.
S. Altrichter, Stefan Frischbutter, J. Fok, P. Kolkhir, Q. Jiao, P. Skov, M. Metz, M. Church, M. Maurer   +8 more
semanticscholar   +1 more source