Results 151 to 160 of about 19,705,637 (288)

Focal intratesticular lesions including spontaneous hematomas in the acute scrotum: the pivotal role of ultrasound and MRI in diagnosis and management-a pictorial review. [PDF]

Insights Imaging
Rocher L, Hijazi M, Shaito F, Hani C, Bekdache O, Arama E, Zaag S.   +6 more
europepmc   +1 more source

Just Between Us [PDF]

, 2019
Romeo, Kamaria
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Characterization of the Complete Genome of <i>Arthrobacter globiformis</i> Cluster FF Bacteriophage QuinnAvery. [PDF]

MicroPubl Biol
Akst EP, Areda D, Battaglioli EJ, Beck CW, Bogush ML, Caruso SM, Cedergren-Healy AM, Chirravuri SV, Crossley DL, D'Amico-Willman K, Delesalle VA, Hare RF, Harris DL, Ingram JR, Karpakakunjaram V, Khatabi B, Klyczek KK, Lawson JN, Leonetti C, Mathews SL, McDonald MT, Mika KM, Morikwe UC, Nikolakis ZL, Purroy XS, Ryan AB, Schiller HS, Sepehri M, Starkey DE, Storks L, Tchedre KT, Vallor AC, Vega NM, Velez-Ramirez DE, Whitaker EE, Williams DC, Young NM, Zagorac CH, Jacobs-Sera D, Monti D, Russell DA, Wise B, Warner MH.   +42 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Influence of ultrasonication power and treatment duration on the functional and structural properties of elephant foot yam starch. [PDF]

Ultrason Sonochem
Medha T, Deepika PS, Selva Kumar T, Vantaku VR, Amanullah M, Devi PB, Vinayagam R, Reddy CK.   +7 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

A Review and Perspective of Techniques for Autonomous Robotic Ultrasound Acquisitions. [PDF]

Sensors (Basel)
Qin Y, Dang L, Ren F, Li Z, Duan L, Wang H, Han J.   +6 more
europepmc   +1 more source