Results 201 to 210 of about 9,659,533 (261)

Comparison of ultrasonography-guided fine-needle aspiration and endoscopic ultrasonography-guided fine needle aspiration for the diagnosis of pancreatic malignancy. [PDF]

Clinics (Sao Paulo)
Jiang S, Zhu Y, Wang P, Wu Z, Chen Y.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Upfront surgery vs. neoadjuvant therapy in pancreatic cancer with venous involvement: a multicenter retrospective analysis. [PDF]

Langenbecks Arch Surg
Halimi A, Zwart ES, Yilmaz BS, Kurlinkus B, Ahola R, Del Chiaro M, Sparrelid E, Rangelova E, Maggino L, Malleo G, Lionetto G, Salvia R, Roberts KJ, Giovinazzo F, Falconi M, Crippa S, Belfiori G, Kazemier G, Maisonneuve P, Laukkarinen J, Ceyhan GO.   +20 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Inter-reader agreement in multimodality imaging of carotid plaque-RADS: considerations for modality selection. [PDF]

Insights Imaging
Zhang J, Yan Y, Xing Y, Bai L, Sa R, Wang L.   +5 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Retromammary Schwannoma Mimicking a Breast Tumor in a Patient with Neurofibromatosis Type 1: A Case Report Demonstrating Surgical Avoidance Using Contrast-Enhanced Ultrasound-Informed Biopsy. [PDF]

Surg Case Rep
Yamazaki H, Kanazawa S, Ozawa K, Yuasa H, Tsuda H.   +4 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Clinicopathological Significance of Ultrasound Risk Features and the Taller-Than-Wide Sign for Tumor Advancement in Differentiated Thyroid Cancer: A Single-Center Analysis. [PDF]

Cancer Manag Res
Miciak M, Jurkiewicz K, Kalka N, Reiner M, Szymański MC, Biernat S, Diakowska D, Kaliszewski K.   +7 more
europepmc   +1 more source