Results 121 to 130 of about 3,807,351 (262)

SARS‐CoV‐2 targets mitochondria, exacerbating COVID‐19 pneumonia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Following entry into airway epithelial cells (AECs), SARS‐CoV‐2 releases its single‐stranded RNA into the cytoplasm, where it is translated into viral proteins. Several of these viral proteins localize to mitochondria and interact with key mitochondrial components.
Danchen Wu   +5 more
wiley   +1 more source

AEC Matador Tractor

open access: yes, 2009
Frank Wilson's AEC Matador box tractor photographed at Oxford St Giles Fair ...
Cawthorne, Ian
core  

Longitudinal Associations Between Inflammation and Multi‐Dimensional Fatigue up to 2 Years After Colorectal Cancer Diagnosis

open access: yesInternational Journal of Cancer, Volume 159, Issue 10, Page 2437-2451, 15 November 2026.
Cancer‐related fatigue (CRF) is a common and debilitating symptom among colorectal cancer (CRC) patients, but its underlying biological causes remain unclear, with inflammation emerging as a leading suspect. Here, researchers analyzed inflammatory biomarkers in blood samples and evaluated responses in fatigue assessments from CRC patients at and up to ...
Anouk E. C. Bruijnzeels   +3 more
wiley   +1 more source

Bridging TG‐116 and TG‐232: A retrospective multi‐vendor evaluation of deviation index re‐centering and process control in digital radiography

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 10, October 2026.
Abstract Background The deviation index (DI) is a vendor‐neutral indicator of detector exposure relative to the configured target exposure index (TEI). Because TEI is a protocol value rather than a calibrated physical quantity, poorly aligned TEI settings can create systematic DI offsets, obscure protocol problems, and prevent meaningful statistical ...
Ezzat AbuAzzah   +11 more
wiley   +1 more source

Orchestrating the metastatic symphony: the role of extracellular vesicles in the epithelial–mesenchymal transition and pulmonary niche formation of breast cancer

open access: yesBiological Reviews, Volume 101, Issue 5, Page 2103-2118, October 2026.
ABSTRACT The complexity of breast cancer (BC) lung metastasis lies in the capacity of tumour cells to interact efficiently with distant organs to promote colonisation, a process that involves the sophisticated coordination of inherent cellular plasticity and the remodelling of the distant microenvironment.
Jian Lu   +12 more
wiley   +1 more source

Amyloid‐Forming Amylin Secreted by the Pancreas Promotes Hypoxia‐Inducible Factor Activation and Mitochondrial Alterations in Liver and Heart During Type 2 Diabetes Pathogenesis

open access: yesComprehensive Physiology, Volume 16, Issue 5, October 2026.
Human amylin is secreted from the pancreas of HIP rats and is amyloidogenic, forming aggregates systemically. In comparison with age‐matched control (WT), hyperglycemic (UCD) and amylin knockout rats (AKO), HIP rats showed increased hypoxia‐inducible factors (HIF‐1/2) in heart and liver, alongside alterations in mitochondrial electron transfer system ...
Alice E. Knapton   +9 more
wiley   +1 more source

The TRPM2–PARP‐1 Axis Involvement in Bisphenol A and Nonylphenol‐Induced Ferroptosis in Trigeminal Ganglion Cells

open access: yesJournal of Applied Toxicology, Volume 46, Issue 10, Page 3660-3674, October 2026.
ABSTRACT Environmental contaminants like bisphenol A (BPA) and nonylphenol (NP) are recognized neurotoxicants; however, the molecular mechanisms underlying their impact on sensory ganglia, specifically the trigeminal ganglion (TG), remain critically underexplored.
Betül Yazğan   +3 more
wiley   +1 more source

Integration of data and processes of AEC projects using the industry foundation classes

open access: yes, 2005
Integration trends in the Architectural, Engineering, and Construction (AEC) industry are increasing the demands for the implementation and deployment of integrated project systems. Much of the research throughout the last decade was driven by the need to develop integrated project systems and standard industry-wide data models to support their ...
Halfawy, M. R., Froese, T.
openaire   +1 more source

Promising Patient‐Engagement Practices Used by National Research Networks at the US Veterans Health Administration: Perspectives of Veterans, Staff, and Research Leaders

open access: yesLearning Health Systems, Volume 10, Issue 4, October 2026.
ABSTRACT Introduction Active involvement of patients is an essential feature of learning health systems and patient‐centered research. Research networks and healthcare organizations lack guidance on best practices for developing and sustaining patient engagement infrastructure.
Tracy L. Sides   +7 more
wiley   +1 more source

Therapeutic potential of a Bax inhibitor‐1/TMBIM6 antagonist (BIA) and its analogues in Aspergillus fumigatus‐induced asthma via dual targeting of AKT and epithelial‐derived inflammatory cytokines

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 19, Page 5975-5991, October 2026.
Background and Purpose Aspergillus fumigatus (A. fumigatus) exposure causes of severe allergic asthma, characterized by airway inflammation and epithelial dysfunction. TMBIM6 (Bax inhibitor‐1) has been implicated in airway epithelial stress responses and AKT signalling.
Young‐Jin Yu   +7 more
wiley   +1 more source

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