Results 141 to 150 of about 312,698 (293)

Replacement-Based Ageing Interventions for Systemic Rejuvenation: Shaping Longevity Science and Clinical Directions. [PDF]

Aging Cell
Olaisen BF, Gladyshev VN, Zhang B, Atala A, Loh KM, Gorbunova V, Rando TA, Wyss-Coray T, Verdin E, Zhavoronkov A, Scheibye-Knudsen M, Lore S, Bakula D.   +12 more
europepmc   +1 more source

Oil drills escape US export control [PDF]

Nature, 1980
openaire   +1 more source

The global transmission of U.S. monetary policy [PDF]

, 2020
Degasperi, Riccardo, Hong, Seokki Simon, Ricco, Giovanni   +2 more
core  

Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl‐tRNA Synthetase Boosts Genetic Code Expansion in E. coli

Advanced Science, EarlyView.
ABSTRACT Orthogonal translation systems (OTSs) enable site‐specific incorporation of non‐canonical amino acids (ncAAs) and are central to genetic code expansion. Current engineering strategies typically rely on hyperstable aminoacyl tRNA synthetase (aaRS) scaffolds to tolerate destabilizing mutations required for substrate diversification.
Nikolaj G. Koch, Peter Goettig, Michael A. Nash, Juri Rappsilber, Nediljko Budisa   +4 more
wiley   +1 more source

Excessive phosphorus loading contributes to future vulnerability of mangrove ecosystems by reducing net ecosystem exchange of carbon. [PDF]

Camb Prism Coast Futur
Krauss KW, Conrad JR, Duberstein JA, Ward EJ, Drexler JZ, Buffington KJ, Benscoter BW, Miller HJ, Faron NT, Merino S, From AS, Peneva-Reed E, Zhu Z, Thorne KM, Feller IC.   +14 more
europepmc   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

Potential economy-wide impacts of an African swine fever outbreak in the United States. [PDF]

Front Vet Sci
de Menezes TC, Countryman AM, Pendell DL, Rushton J, Tickel J, Simmons H.   +5 more
europepmc   +1 more source

Managers' Mobility, Trade Status and Wages [PDF]

This paper investigates whether the arrival of managers with export experience, i.e. experience acquired through participation in the export activity of previous employers, is related to firms' international trade status and to what extent this ...
Giordano Mion, Luca David Opromolla
core  

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source

WDR72 Regulates Microtubule-Associated Vesicular miRNA Export in Ameloblasts During Enamel Maturation. [PDF]

Calcif Tissue Int
Duong T, Ngu J, Katsura KA, DenBesten P, Nakano Y.   +4 more
europepmc   +1 more source