Robust single-molecule tracking of RNA abundance and dynamics via TSSOT. [PDF]
Luo Y +10 more
europepmc +1 more source
The US Policy of Export Control towards Communist Bloc
openaire +1 more source
Oil‐Coated Nanoplastics Induce Rapid Membrane Disruption and Severe Intestinal Injury
Oil‐rich food contact dramatically amplifies MNP release from plastic takeout containers, producing oil‐coated nanoplastics with altered surface properties and rapid membrane‐disruptive effects. These particles cause severe intestinal barrier damage and immune dysfunction in mice, and risk modeling suggests that long‐term gastrointestinal burdens may ...
Ruwen Xie +17 more
wiley +1 more source
Rapid disassembly and Piwi-independent reassembly of <i>Drosophila</i> piRNA cluster heterochromatin following acute heat shock. [PDF]
Rice NP, Ho S, Weng Z, Theurkauf WE.
europepmc +1 more source
HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li +13 more
wiley +1 more source
Managing technological sovereignty: a systematic review of semiconductor industry policy and regional ecosystem governance. [PDF]
Cai J +6 more
europepmc +1 more source
US-EC dispute over the gas pipeline from Siberia to Western Europe. Comments of the European Community on the Amendments of 22 June 1982 to the U.S. Export Regulations. "EC Calls for Withdrawal of US. Pipeline Sanctions", European Community News No. 23/1982, 12 August 1982 [PDF]
core
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi +13 more
wiley +1 more source
A novel <i>de novo ATP2B1</i> variant causes autosomal dominant intellectual developmental disorder 66 by disrupting calcium homeostasis via impaired membrane trafficking. [PDF]
Zang H, Yang X, Liu Y, Ma C, Yang D.
europepmc +1 more source
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu +10 more
wiley +1 more source

