Results 141 to 150 of about 2,478,838 (311)
K21 education and intelligent sciences: future schools and teachers/students in future society
The further development of intelligent science and technology will inevitably transform the knowledge infrastructure of society, compelling us to reorganize the K21 education system—from early childhood to doctoral stages—using new thinking and new ...
Fei-Yue WANG
doaj
Rental Housing Costs in Buffalo [PDF]
This fact sheet summarizes the data currently available on the changing costs of rental housing in Buffalo, NY. It explores six data sources for rent figures and what each one can tell us about Buffalo’s rental market. The sources include U.S.
Wooton, Sarah
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
The tendency of organizations is to achieve positioning and legitimacy through strategies of corporate social responsibility (CSR). This article focuses on the analysis of CSR practices and it seeks, through a business case, to define a method to examine
Diana Carolina Peláez Villada +1 more
doaj
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Building Trust: Communication and Subordinate Trust in Public Organizations
This research explores how communication strategies of supervisors in public organizations influence subordinates’ trust in their supervisors and organization.
Greg PORUMBESCU +2 more
doaj
US Organ Procurement Organization Donation Principles, Laws, and Practices [PDF]
Mone, Thomas, Danovitch, Gabriel
openaire +2 more sources
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source

