Results 61 to 70 of about 2,478,838 (311)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Refugees, Internally Displaced Persons, And International Humanitarian Law [PDF]

open access: yes, 2004
The fact that war is the primary cause of people being uprooted prompts us to ask what protection the law of armed conflict affords refugees and displaced persons. How does humanitarian law protect groups of civilians from being forced to flee?
Bugnion, Francois
core   +1 more source

Broadcasting graphic war violence: the moral face of Channel 4 [PDF]

open access: yes, 2013
Drawing on empirical data from Channel 4 (C4) regarding the broadcasting of violent war imagery, and positioned within Goffman’s notion of the interaction ritual (1959, 1967), this article investigates how C4 negotiate potentially competing commercial ...
BBC2   +24 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

An Alternative to Temporary Staffing: Considerations for Workforce Practitioners [PDF]

open access: yes, 2012
The temporary staffing industry has become a fixture of the US economy in recent decades, and workforce practitioners are increasingly noting the prevalence of temporary jobs in the low-skilled labor market. To ensure that these jobs are a stepping stone
Deena Schwartz   +3 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Beyond Deliberation: A Strategy for Civic Renewal

open access: yesJournal of Deliberative Democracy, 2014
To expand opportunities for discussion and reflection about public issues, we should look beyond the organizations that intentionally convene deliberations and also enlist organizations that preserve common resources, volunteer service groups, civics ...
Peter Levine
doaj   +2 more sources

What Works and Looking Ahead: A Comparative Study of UK and US Policies and Practices Facilitating Return to Work for People with Disabilities [PDF]

open access: yes, 2003
Independent research organizations in the US and the UK were commissioned to review the research on ‘what works’ in facilitating return to work for people with disabilities, and to consider current developments in the light of the evidence. They produced
Bruyere, Susanne M, Dr.   +4 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Celebrating Diversity through Spirituality in the Workplace: Transforming Organizations Holistically [PDF]

open access: yes, 2019
Managing diversity effectively is the key to attract and retain a productive workforce. Research demonstrates that celebrating diversity leads to greater productivity, increased creativity, and heightened morale and motivation.
Dhiman, Satinder K.   +2 more
core   +1 more source

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