Results 81 to 90 of about 2,478,838 (311)

Process innovation in tourism management: A review of the literature

open access: yesIntangible Capital, 2015
Purpose: Identifying gaps in the academic literature regarding three great management topics: Process Innovation, Tourism Management and Process Innovation in Tourism Management in order to establish the conceptual framework and identify future lines of ...
Irma Elia Damian   +1 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Investigation of New Hampshire hydropower potential [PDF]

open access: yes, 2012
The popularity of green and renewable energy has risen sharply in recent years, and hydropower has consistently been the most common form of renewable energy in both the US and the state of New Hampshire.
Murray, Maxwell
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Organic synthetic transformations using organic dyes as photoredox catalysts

open access: yesOrg. Biomol. Chem., 2014
This review article presents various photocatalytic transformation such as oxygenation, halogenation and C–C bond formation with organic photoredox catalysts.
Shunichi, Fukuzumi, Kei, Ohkubo
openaire   +3 more sources

The Endowment Challenge [PDF]

open access: yes, 2013
The financial crisis of 2008 is nearly five years behind us, yet its impact on nonprofit organizations persists. The bull market that began in the early 1980s delivered historically strong returns for most long-term investment portfolios through 2008 ...

core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Fundraising Bright Spots: Strategies and Inspiration from Social Change Organizations Raising Money from Individual Donors [PDF]

open access: yes, 2016
"Let's find an outside expert who can help." It's a natural impulse in the search for answers to the chronic fundraising challenges facing so many nonprofit organizations. But what if the real answers were already all around us?
Jeanne Bell, Kim Klein
core  

Requirements for effective participation in self-constructed organizations [PDF]

open access: yes, 1996
This is an article about effective participation in organizations. It offers insights about the interplay between individual action and organization structure.
Beer   +10 more
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

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