Results 101 to 110 of about 119,123 (311)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Usability evaluation of a locomotor therapy device considering different strategies

open access: yesCurrent Directions in Biomedical Engineering, 2016
Usability of medical devices is one of the main determining factors in preventing use errors in treatment and strongly correlates to patient safety and quality of treatment. This thesis demonstrates the usability testing and evaluation of a prototype for
Langthaler Sonja   +3 more
doaj   +1 more source

A case study on integrating contextual information with analytical usability evaluation

open access: yes, 2002
The work reported here integrates an analytical evaluation technique, Programmable User Modelling, with established knowledge elicitation techniques; the choice of techniques is guided by a selection framework, ACRE.
Rugg, G, Blandford, A
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Towards a validated glossary of usability attributes for the evaluation of wearable robotic devices

open access: yesJournal of NeuroEngineering and Rehabilitation
Background Despite technical advances in the field of wearable robotic devices (WRD), there is still limited user acceptance of these technologies. While usability often comes as a key factor influencing acceptance, there is a scattered landscape of ...
Diana Herrera-Valenzuela   +5 more
doaj   +1 more source

Usability and open source software.

open access: yes, 2002
Open source communities have successfully developed many pieces of software although most computer users only use proprietary applications. The usability of open source software is often regarded as one reason for this limited distribution. In this paper
Nichols, David M., Twidale, Michael B.
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Principles in Patterns (PiP) : Heuristic Evaluation of Course and Class Approval Online Pilot (C-CAP)

open access: yes, 2011
The PiP Evaluation Plan documents four distinct evaluative strands, the first of which entails an evaluation of the PiP system pilot (WP7:37). Phase 1 of this evaluative strand focuses on the heuristic evaluation of the PiP Course and Class Approval ...
Macgregor, George
core  

The construction and validation of a usability evaluation survey for mobile learning environments

open access: yes
The advent of mobile technologies in learning context, has been increased the requirements for developing appropriate usability model to align with mobile learning applications.
Nadia Parsazadeh, Rosmah Ali, Mehran Rezaei, Sanaz Zolfaghar Tehrani
core   +1 more source

Social personalized adaptive e-learning environment : Topolor - implementation and evaluation [PDF]

open access: yes
This paper presents a quantitative study on the use of Topolor - a prototype that introduces Web 2.0 tools and Facebook-like appearance into an adaptive educational hypermedia system.
Al Qudah, Dana   +4 more
core   +1 more source

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