Results 131 to 140 of about 491,007 (324)

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

USABILITY TESTING SISTEM PADA E-ACADEMIC POLITEKNIK HARAPAN BERSAMA

open access: yesEmitor: Jurnal Teknik Elektro, 2016
Layanan publik yang berbasiskan web saat ini sudah menjadi bagian yang sangat penting dalam menunjang keberhasilan dari suatu instansi pendidikan,  akan tetapi layanan yang berbasiskan web masih banyak yang kesulitan dalam menggunakannya, bahkan tidak ...
Dega Surono Wibowo
doaj  

Usability Testing of Interactive Multimedia Services [PDF]

open access: yes, 2000
Interactive mu ltimedia services, such as video-on-demand offered to the public at home need to be tested carefully for usability. The environment as well as users is heterogeneous and they use different input and output devices than with a personal ...
Ebba Thora Hvannberg   +1 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Qualitative Marketing Research Through Usability Testing [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2008
Usability is an attribute of any good product, just as its functionality. It refers mainly to the utility of a product for its indented users, as well as to its ease of use. And whilst a correct functionality is critical for the commercial success of any
Orzan Mihai   +2 more
doaj  

TRANSLATOR APPLICATIONS MESSENGER JAVA BASED AND GOOGLE TRANSLATE API [PDF]

open access: yes, 2013
The purpose of this research is to produce a messenger applications such as Messenger Translator Applications. Then test the feasibility of the application as an application that makes it easy to translate language or translator in chat communication ...
Novita, Anindita
core  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

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