Results 131 to 140 of about 5,877,092 (294)

Water Footprint Accounting Along the Wheat-Bread Value Chain: Implications for Sustainable and Productive Water Use Benchmarks

, 2018
Efficient and wise management of freshwater resources in South Africa has become critical because of the alarming freshwater scarceness. The situation requires a thorough examination of how water is utilized across various departments that use water ...
Pascalina Matohlang Mohlotsane, Enoch Owusu-Sekyere, Leon Daniel Van Rensburg, Henry Jordaan, Jonannes Hendrikus Barnard   +4 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

The Effect of Knowledge Miscalibration on the Dimensions of Consumer Value [PDF]

, 2015
Consumer value is an important determinant of consumers’ post-use behaviour, for example satisfaction, repeat purchase and word of mouth. The existing research mainly looks at the factors associated with the product and service providers to improve ...
Razmdoost, Kamran
core  

Use-value assessment and land conservation

California Agriculture, 1977
There is no evidence that the California Land Conservation Act of 1965 has “conserved” agricultural land.
H Carman, C Heaton
doaj  

How Should Global Fund Use Value-for-Money Information to Sustain its Investments in Graduating Countries? [PDF]

Int J Health Policy Manag, 2017
Kanpirom K, Luz ACG, Chalkidou K, Teerawattananon Y.   +3 more
europepmc   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Use-value and importance of socio-cultural knowledge on Carapa procera trees in the Sudanian zone in Mali. [PDF]

J Ethnobiol Ethnomed, 2015
Dembélé U, Lykke AM, Koné Y, Témé B, Kouyaté AM.   +4 more
europepmc   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source