Results 201 to 210 of about 518,430 (330)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Patients' Expectations for App-Based Therapy in Knee Osteoarthritis: User-Centered Design Approach. [PDF]

JMIR Rehabil Assist Technol
Krištof Mirt P, Erjavec K, Krsnik S, Kotnik P, Mohsen H.   +4 more
europepmc   +1 more source

User-Centered Design

, 2017
Doroftei, Daniela, Cubber, Geert De, Wagemans, Rene, Matos, Anibal, Silva, Eduardo, Lobo, Victor, Cardoso, Guerreiro, Chintamani, Keshav, Govindaraj, Shashank, Gancet, Jeremi, Serrano, Daniel   +10 more
openaire   +3 more sources

EDTF: A User-Centered Approach to Digital Educational Games Design and Development [PDF]

Raluca Ionela Maxim, Joan Arnedo-Moreno
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Stress and Well-Being Intervention and mHealth Delivery Adaptation for Latinx Millennial Caregivers: Qualitative User-Centered Design Approach. [PDF]

JMIR Nurs
Thomas Hebdon M, Dupree GD, Hernandez J, Cuevas H, Thomas M, Burt S, Peterson N, Horner SD.   +7 more
europepmc   +1 more source

Development of Information and Management System of Student Competition Groups through User-Centered Design Approach

, 2023
Dinan Yulianto, Ahmad Raditya Cahya Baswara, Lugas Alhawariy, Marina Indah Prasasti, Gema Antika Hariadi   +4 more
openalex   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Leveraging User-Centered Design and Usability and Skills Testing for a Novel Diabetes Survival Skills Toolkit. [PDF]

J Endocr Soc
Freeman S, Lecka L, Davis K, Prince G, Carthy K, Seley JJ, Song J, Lee J, Bailey SC, Khorzad R, Gatchell D, Ankenman B, Lewis DR, Holl JL, Wallia A.   +14 more
europepmc   +1 more source

Using the NIATx Model to Implement User-Centered Design of Technology for Older Adults [PDF]

, 2016
David H. Gustafson, Adam Maus, Julianne Judkins, Susan Dinauer, Andrew Isham, Roberta Ann Johnson, Gina Landucci, Amy K. Atwood   +7 more
openalex   +1 more source