Results 71 to 80 of about 665,180 (356)

User needs and design features of sanitation digital solutions in Kawempe division, Kampala Uganda: a user centered design approach

open access: yesFrontiers in Public Health, 2023
Despite improvements in access to water and sanitation services globally, a significant population in Sub Saharan Africa has limited access to improved sanitation facilities.
Comfort Hajra Mukasa   +4 more
doaj   +1 more source

Latin Hypercubes and Space-filling Designs [PDF]

open access: yesHandbook of Design and Analysis of Experiments, Bingham, D., Dean, A., Morris, M., and Stufken, J. ed. 593-626, CRC Press (2015), 2022
This chapter discusses a general design approach to planning computer experiments, which seeks design points that fill a bounded design region as uniformly as possible. Such designs are broadly referred to as space-filling designs.
arxiv  

Incentive-Centered Design for User-Contributed Content [PDF]

open access: yes, 2012
We review incentive-centered design for user-contributed content (UCC) on the Internet. UCC systems, produced (in part) through voluntary contributions made by non-employees, face fundamental incentives problems.
Jian, Lian, MacKie-Mason, Jeffrey K.
core   +1 more source

A histidine‐rich extension of the mitochondrial F0 subunit ATP6 from the ice worm Mesenchytraeus solifugus increases ATP synthase activity in bacteria

open access: yesFEBS Letters, EarlyView.
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley   +2 more
wiley   +1 more source

User interface and user experience analysis of Kejar Mimpi mobile application using the User-Centered Design method

open access: yesIlkom Jurnal Ilmiah, 2023
User criticism on the Play Store revealed some flaws in the Kejar Mimpi App review. Observations were made on research that discussed the Kejar Mimpi Application, and it discovered that no prior research on User Experience and User Interface had been ...
Brigitha Valensia Angela   +4 more
doaj   +1 more source

Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions

open access: yesFEBS Letters, EarlyView.
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten   +10 more
wiley   +1 more source

Design Spaces and How Software Designers Use Them: a sampler [PDF]

open access: yesIn Proceedings of the 1st International Workshop on Designing Software (Designing '24), 2024. Association for Computing Machinery, New York, NY, USA, pp. 1-8
Discussions of software design often refer to using "design spaces" to describe the spectrum of available design alternatives. This supports design thinking in many ways: to capture domain knowledge, to support a wide variety of design activity, to analyze or predict properties of alternatives, to understand interactions and dependencies among design ...
arxiv   +1 more source

Evaluating Mixed-Initiative Procedural Level Design Tools using a Triple-Blind Mixed-Method User Study [PDF]

open access: yes, 2020
Results from a triple-blind mixed-method user study into the effectiveness of mixed-initiative tools for the procedural generation of game levels are presented. A tool which generates levels using interactive evolutionary optimisation was designed for this study which (a) is focused on supporting the designer to explore the design space and (b) only ...
arxiv   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

open access: yesFEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung   +6 more
wiley   +1 more source

Augmented Reality Chemical Reaction with User-Centered Design

open access: yesMATEC Web of Conferences, 2018
One of chemistry is the chemical element that is represented by the symbol on the periodic table. The low level of activity, interest, and the result of chemistry learning in school is caused by the students generally having difficulty in solving ...
Nurpandi Finsa, Gumelar Agung
doaj   +1 more source

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