Results 111 to 120 of about 603,022 (311)

An aerospace component cost modelling study for value driven design [PDF]

, 2009
Demand is increasing in aero-engine products for better efficiency and environmental performance whilst keeping the cost low. Unlike performance, the physics behind cost is least understood.
Cheung, J. M. W., Wiseall, S.S., Scanlan, J. P., Wiseall, S. S., Cheung, J.M.W., Scanlan, J.P.   +5 more
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Integrating Gamification with Demand-Responsive Transportation: An Approach to User-Driven Optimisation

ADCAIJ: Advances in Distributed Computing and Artificial Intelligence Journal
The successful implementation of demand-responsive transportation services is often hindered due to difficulties associated with economic viability. With the aim of reducing service operational costs and environmental impact, this paper proposes an architecture that enables user-driven optimisation through the modification of their travel preferences ...
Martí, Pasqual, Jordán, Jaume, Julian, Vicente, Okre a-Duric, Bogdan, Schatten, Markus   +4 more
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

An Ontology-Driven Framework for Personalised Context-Aware Running Event Recommendations

Computers
Sport tourism has experienced significant growth within the tourism industry, driven by the increasing demand of special interest tourists to watch or participate in sports events with local sightseeing.
Adisak Intana, Kuljaree Tantayakul, Wasupon Tanthavanich, Wachiravit Chumchuay   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Two-Hemisphere Model Driven Approach: Engineering Based Software Development

Several model driven approaches are currently used and developed, namely, generic model driven approaches, agile model driven approaches, business process model driven approaches, etc.
Ņikiforova, Oksana, Kirikova, Mārīte
core  

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Are disruptive agricultural technologies compatible with agroecology?

npj Sustainable Agriculture
Agroecology has emerged as a credible approach to achieving sustainable and resilient agrifood systems. But the role for disruptive agricultural technologies within agroecology remains contentious.
Helena Shilomboleni, Matthew A. Schnurr
doaj   +1 more source