System quality, user satisfaction and end user development
, 1999 Organisations rely heavily on user developed applications (UDAs) to support organisational decision making, but for the most part the satisfaction of the user developer is the sole indicator of application success.
Payne, C. +6 more
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Artificial Intelligence Discontinuation Effects (AI-DICE): An Emerging Phenomenon in Mental Health Applications. [PDF]
JMIR AIKelly MM, Moore PS, Zai AH, Allison J.
europepmc +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
REGIONAL ECONOMIC IMPACTS OF REDUCTIONS IN FISHERIES PRODUCTION: A SUPPLY-DRIVEN APPROACH
Much debate and subsequent confusion have recently been generated regarding the economic importance of the longline fisheries for tuna and swordfish in Hawaii.
Leung, PingSun, Pooley, Samuel G.
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A formalized object oriented user driven approach using business forms
, 1994 Although object-orientation exhibits many promises, there exists many fundamental areas that need to be addressed. Two of these areas are the widespread acceptance of the object mindset, and interactive user involvement in the object oriented business ...
Jentzsch, Ric
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Design and impact of gamification, theory-driven frameworks, and human-centered design in mobile health applications for preconception care: A systematic review protocol. [PDF]
J Educ Health PromotMuhamad Rusdi NDS +3 more
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
User participation and user satisfaction in information systems development
, 2001 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 26/06/2001.Information Systems (IS) are being developed and used in organizations to achieve their business goals and to enhance organizational ...
Bokhari, Rahat Hussain, Bokhari, R.H.
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