Results 131 to 140 of about 520,800 (300)
E-Catalog Promotion of Fishermen Business Group with User Centered Design Method
JISA (Jurnal Informatika dan Sains)This research aims to design a promotional e-catalog for fishing business groups using the User Centered Design (UCD) method to improve the quality of their promotional services online.
Muchamad Fajri Amirul Nasrullah +4 more
doaj +1 more source
Android Based Minang Language Using UCD Method (User Centered Design): Tour Guide Application [PDF]
, 2018 UCD (User Centered Design) is a design philosophy of putting users at the center of a system development process. The difficulties experienced by the tourists who visited West Sumatra during traveling is in communicating which can be helped by using UCD ...
Munthe, I. R. (Ibu) +3 more
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Bridging User-Centered Design and Requirements Engineering with GRL and Persona Cases [PDF]
, 2011 Despite the large body of i* research, there has been com- paratively little work on how goal-modelling techniques can help identify usability concerns. Recent work has considered how goal models might better integrate with User-Centered Design.
Faily, Shamal
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Harmonizing design and desire: Unveiling user-centered requirements for university buildings
Results in EngineeringThe design of university buildings plays a critical role in users' productivity, health, and behavior. The design should incorporate end users' and architects' perceptions to prevent decreased satisfaction, productivity, and health issues.
Mohamed Yasser Arafat +3 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source