Results 101 to 110 of about 37,804 (303)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Road User Charges in Britain [PDF]

open access: yes
At present the Department of Transport allocates road use costs according to concepts of fair attribution, and road user charges for commercial vehicles are intended to cover these costs. The paper calculates the efficient road user charge - the marginal
Newbery, David M G
core  

Open data – an introduction to the issue

open access: yesITM Web of Conferences, 2018
Rapidly developing of internet technologies and digitalization of government generate more and more data. Databases from various public institutions and private sectors, e.g.
Dymora Paweł   +2 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

User charges for health care in developing countries : a review of the economic literature [PDF]

open access: yes, 1993
Literature suggests that in theory, the efficiency of user charges for health services is related to the level of externality, the price elasticity of demand, the proportion of total costs which are private access costs, and the level of the government ...
McPake, Barbara
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Public sector pricing in a fiscal context [PDF]

open access: yes
Administered prices should deviate from marginal cost if they are to be used as instruments to generate revenue. The analysis is based on the Bank's two-step approach to public sector pricing: first calculating marginal cost, and then adjusting it to ...
Heady, Christopher
core  

Charging for external users [PDF]

open access: yes, 2001
Describes the creation of and application of a formula for calculating the cost of borrowing by external users.
openaire  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Tax Competition, Excludable Public Goods and User Charges [PDF]

open access: yes, 2004
This paper provides an economic explanation for the increasing reliance of the state on revenue from user charges on excludable public goods. We develop a model with many identical countries.
Huber, Bernd, Runkel, Marco
core  

Home - About - Disclaimer - Privacy