Results 41 to 50 of about 204,997 (268)
Jurnal Sarjana Teknik Informatika, 2020 Salah satu bentuk kemajuan pesat dari pengelolaan koleksi tugas akhir, skripsi, tesis maupun disertasi di perpustakaan perguruan tinggi (PT) di Indonesia adalah dengan tersedianya koleksi tersebut dalam format elektronik (eThesis).
Angga Ibnu Barata, Ardiansyah Ardiansyah
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Design of OpenFOAM solver client based on service architecture
Dianzi Jishu Yingyong, 2023 Aiming at the problem that the OpenFOAM solving software lacks GUI function, the user interaction experience is poor, this paper studies and designs an OpenFOAM solving client software.
Ma Yicong, Mou Hongyu, Huai Xiaoyong
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Statistical User Interfaces [PDF]
, 2011 A statistical user interface is an interface between a human user and a statistical software package. Whenever we use a statistical software package we want to solve a specific statistical problem. But very often at first it is necessary to learn specific things about the software package.
openaire +2 more sources
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Graphic user interface for synchrotron beamline
NOVASINERGIA, 2019 This research consisted of developing a graphical user interface in Python language for the reconstruction of images based on the propagation technique (PBI).
Jose Brito del Pino +3 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source