Results 61 to 70 of about 204,997 (268)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Workflow User Interfaces Patterns

Acta Universitaria, 2012
Este trabajo presenta una colección de patrones de diseño de interfaces de usuario para sistemas de información para el flujo de trabajo; la colección incluye cuarenta y tres patrones clasificados en siete categorías identificados a partir de la lógica ...
Jean Vanderdonckt, Juan Manuel González-Calleros, Josefina Guerrero-García   +2 more
doaj  

Person-centered hospital care in Indonesia: the role of digital health competency, user interface quality, and user experience in a multi-hospital study

Frontiers in Health Services
IntroductionHospital digitalization is expected to strengthen person-centered care, yet the everyday experience of healthcare workers depends on both digital readiness and the usability of the systems they operate.
Enny Rachmani, Evina Widiawati, Deshinta Arrova Dewi, Syed Abdul Shabbir, Fu-Yu Chen, Arif Kurniadi, Sylvia Anjani, Eti Rimawati, M. G. Catur Yuantari, Amiq Fahmi   +9 more
doaj   +1 more source

The usability of ventilator maintenance user interface: A comparative evaluation of user task performance, workload, and user experience

Science Progress, 2020
Poor usability designed of ventilator user interface can easily lead to human error. In this study, we evaluated the usability design of ventilator maintenance user interface and identified problems related to the usability of user interface that could ...
Mingyin Jiang, Dongjie Sun, Qiang Li, Daoxiong Wang   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Database Graphic User Interface correspondence with Ellis Information Seeking behavior Model

Iranian Journal of Information Processing & Management, 2010
Graphic User interface serves as a bridge between man and databases. Its primary purpose is to assist uses by establishing interaction with computer systems.
Muhammad Azami, Rahmatullah Fatahi
doaj  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

William Gibson's Neuro-Metaphor of User Interface

Галактика медиа: журнал медиа исследований
The authors actualize the problem of studying neuro-metaphor as an element of the user interface human-computer. By analyzing the epistemological boundaries of the concepts information and interface in theoretical discussions of the philosophy of science
Gennady V. Bakumenko, Igor S. Baklanov, Olga A. Baklanova   +2 more
doaj   +1 more source