Results 61 to 70 of about 2,901,480 (286)

Statistical User Interfaces [PDF]

, 2011
A statistical user interface is an interface between a human user and a statistical software package. Whenever we use a statistical software package we want to solve a specific statistical problem. But very often at first it is necessary to learn specific things about the software package.
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

RelateGateways: A User Interface for Spontaneous Interaction with Pervasive Services [PDF]

, 2007
RelateGateways is a user interface and system that supports end-user discovery of and interaction with services dynamically encountered in their immediate environment.
Guinard, Dominique, Gellersen, Hans, Streng, Sara   +2 more
core   +4 more sources

Aalto Interface Metrics (AIM): A service and codebase for computational GUI evaluation [PDF]

, 2018
Aalto Interface Metrics (AIM) pools several empirically validated models and metrics of user perception and attention into an easy-to-use online service for the evaluation of graphical user interface (GUI) designs.
Oulasvirta, A., Todi, K., Miniukovich, A., Weinkauf, Tino,, Langerak, T., Koch, Janin, Todi, Kashyap, Koch, J., Laine, M., Palmas, Gregorio,, Laine, Markku, Langerak, Thomas, Kristhombuge, Manoj, Zhu, Yuxi, Oulasvirta, Antti, Miniukovich, Aliaksei, De Pascale, S., Palmas, Gregorio, Kristhombuge, M., De Pascale, Samuli, Jokinen, Jussi, Weinkauf, Tino, Zhu, Y., Jokinen, J.   +23 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Intelligent user interfaces for mobile computing [PDF]

, 2008
In this chapter, the practical issue of realizing a necessary intelligence quotient for realizing Intelligent User Interfaces (IUIs) on mobile devices is considered.
O'Hare, G. M. P. (Greg M. P.), O'Grady, Michael J.   +1 more
core   +1 more source

Graphic user interface for synchrotron beamline

NOVASINERGIA, 2019
This research consisted of developing a graphical user interface in Python language for the reconstruction of images based on the propagation technique (PBI).
Jose Brito del Pino, Felipe Brito del Pino, Moshe Brito del Pino, Diego Reina   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source