Results 71 to 80 of about 3,312,093 (238)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

MODEL-BASED APPROACH TO USER INTERFACE DEVELOPMENT

open access: yesСтатистика и экономика, 2016
One of the main problems of model-driven user interface development approach is the complexity of the development of tools that maintain this methodology at all stages of the software lifecycle.
Anna А. Pupykina, Anna E. Satunina
doaj   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

IM2L: A user interface description language supporting electronic annotation

open access: yes, 2004
The user interface description language IM2L (Interaction Multimodal Markup Language) - an XML compliant language - is introduced and its interpreter is discussed. The design of IM2L is motivated by the need to support the activity of electronic document
Fresta G, Fogli D, Mercante A, Mussio P
core  

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

A generic user interface for energy management in smart homes

open access: yesEnergy Informatics, 2018
Building operating systems play an important role in monitoring energy consumption of devices and improving energy efficiency in household buildings.
Huiwen Xu   +3 more
doaj   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim   +4 more
wiley   +1 more source

User-Interface Metaphors in Theory and Practice

open access: yes, 2003
User-interface metaphors are a widely used, but poorly understood, technique employed in almost all graphical user-interfaces. Although considerable research has gone into the applications of the technique, little work has been performed on the analysis ...
Barr, Pippin (11637400)   +2 more
core   +1 more source

User interface design for keyframe-based content browsing of digital video [PDF]

open access: yes, 2001
With the technological advancements in computing and networking today, many interesting and potentially useful applications are being developed and turned into products.
Lee, Hyowon
core   +2 more sources

Workflow User Interfaces Patterns

open access: yesActa Universitaria, 2012
Este trabajo presenta una colección de patrones de diseño de interfaces de usuario para sistemas de información para el flujo de trabajo; la colección incluye cuarenta y tres patrones clasificados en siete categorías identificados a partir de la lógica ...
Jean Vanderdonckt   +2 more
doaj  

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