Results 71 to 80 of about 204,997 (268)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Uma abordagem baseada em XML para construção de Interfaces de Usuário para Múltiplos Dispositivos = A XML-based approach for building multi-device user interfaces

Acta Scientiarum: Technology, 2006
O desenvolvimento de aplicações para múltiplos dispositivos leva emconsideração diferentes características e restrições de cada dispositivo. Linguagens de especificação de interfaces e modelos arquiteturais têm sido utilizados por projetistas de ...
Ayslan Trevizan Possebom, Antonio Mendes da Silva Filho, Sérgio Roberto Pereira da Silva   +2 more
doaj  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

The Role of Tangible Interfaces in Enhancing Children's Engagement in Learning

MATEC Web of Conferences, 2018
This paper presents the results of an exploratory study in which the authors investigated the impact of tangible interface used by children at the elementary school level.
Rante Hestiasari, Lund Michael, Caliz Doris   +2 more
doaj   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Usability Analysis of the IBOSS PTSP BP Batam User Interface Using Heuristic Evaluation

Journal of Information Systems and Informatics
This research investigates user dissatisfaction with the IBOSS user interface, reported by 54% of users in an initial survey, and aims to improve the interface through heuristic evaluation and subsequent redesign using Gestalt principles.
Bintang Febrian Alamandha, Rina Yulius
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

EVALUASI USABILITY WEBSITE PRODUK ORGANIK DENGAN METODE SYSTEM USABILITY SCALE

J@ti Undip: Jurnal Teknik Industri
Peran User Interface (UI) dan User Experience (UX) sangat penting dalam meningkatkan kemudahan penggunaan dan kepuasan pengguna website. Permasalahan utama penelitian ini adalah ketidakpastian faktor usability yang paling berpengaruh terhadap persepsi ...
Aisyah Sifa Nabila, Ratih Setyaningrum
doaj   +1 more source