Results 61 to 70 of about 11,486,573 (279)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

A user experience map design method based on emotional quantification of in-vehicle HMI

Humanities & Social Sciences Communications, 2023
The emotional experience of the driver is influenced by the design of the in-vehicle interaction interface. User experience journey maps are commonly used by designers to reveal interface design pain points and refine user needs, and further studies are ...
Faren Huo, Yeying Zhao, Chunlei Chai, Fei Fang   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Físchlár on a PDA: handheld user interface design to a video indexing, browsing and playback system [PDF]

, 2001
The Físchlár digital video system is a web-based system for recording, analysis, browsing and playback of TV programmes which currently has about 350 users.
Murphy, Noel, O'Connor, Noel E., Marlow, Seán, Smeaton, Alan F., Lee, Hyowon   +4 more
core   +2 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

UI/UX Design Using Design Thinking Method Based on Website Unload Repair

JISA (Jurnal Informatika dan Sains)
Unload Repair is a PC repair service that can solve problems with computers or laptops. However, the current problem is that marketing through social media tends to be a little bit about information about service services, making it difficult for ...
Anggiet Harjo Baskoro Bonari, Fajar Ariya Putra   +1 more
doaj   +1 more source

Does Color Matter on Web User Interface Design

CommIT Journal, 2017
Emotional advertising on the Internet such as websites and social media can be highly beneficial for Small Medium Enterprises (SMEs). However, not all of SMEs have a website that meets all of the principles of website design which are persuasive ...
Wirania Swasty, Andreas Rio Adriyanto
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

DEPLOYMENT OF A DEEP LEARNING MODEL TO ASSIST PATHOLOGISTS WITH DONOR KIDNEY BIOPSY EVALUATION

Journal of Pathology Informatics, 2022
Joseph Gaut, Jon Marsh, S. Joshua Swamidass, Rick Berry, Victoria Swamidass, Mike Blackford   +5 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source