Results 61 to 70 of about 202,245 (312)
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
الاكاديمي, 2018 The interactive websites are the interaction between the product and the user, and interactive design is based on the user interface for communication and how the interface responds to the user and how to help him to achieve his goals and enjoy the use ...
Abbas Fadhil Abd Al Zahra
doaj +1 more source
Cultural-based Interface Design [PDF]
, 2019 With expanding the internet all around the world, the importance of considering different users with different cultural backgrounds getting more vital.
Tabandehpour, Hossein
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Does Color Matter on Web User Interface Design
CommIT Journal, 2017 Emotional advertising on the Internet such as websites and social media can be highly beneficial for Small Medium Enterprises (SMEs). However, not all of SMEs have a website that meets all of the principles of website design which are persuasive ...
Wirania Swasty, Andreas Rio Adriyanto
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
UI/UX Design Using Design Thinking Method Based on Website Unload Repair
JISA (Jurnal Informatika dan Sains)Unload Repair is a PC repair service that can solve problems with computers or laptops. However, the current problem is that marketing through social media tends to be a little bit about information about service services, making it difficult for ...
Anggiet Harjo Baskoro Bonari +1 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Investigating user preferences in utilizing a 2D paper or 3D sketch based interface for creating 3D virtual models [PDF]
, 2014 Computer modelling of 2D drawings is becoming increasingly popular in modern design as can be witnessed in the shift of modern computer modelling applications from software requiring specialised training to ones targeted for the general consumer market ...
Camilleri, Daniel +5 more
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