Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Perancangan User Interface Sistem Informasi Penjadwalan Kapal Menggunakan Human Centered Design [PDF]
, 2023 The use of information technology can have a major impact in supporting various aspects of human needs and activities, one of which is in the sea transportation sector.
Fajrianur, Muhamad Bima
core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Workflow User Interfaces Patterns
Acta Universitaria, 2012 Este trabajo presenta una colección de patrones de diseño de interfaces de usuario para sistemas de información para el flujo de trabajo; la colección incluye cuarenta y tres patrones clasificados en siete categorías identificados a partir de la lógica ...
Jean Vanderdonckt +2 more
doaj
A software toolkit for web-based virtual environments based on a shared database [PDF]
, 2004 We propose a software toolkit for developing complex web-based user interfaces, incorporating such things as multi-user facilities, virtual environments (VEs), and interface agents.
Dijk, E.M.A.G. van +2 more
core +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
An empirical investigation into the preferences of the elderly for user interface design in personal electronic health record systems. [PDF]
Front Digit Health, 2023 Zhang S, Song J.
europepmc +1 more source
PERANCANGAN DESIGN SYSTEM PADA WEBSITE TRAVEL MOBIL DENGAN METODE ATOMIC DESIGN [PDF]
Car rental provides daily or contract car rental services with driver or keyless options. This can be a solution for students in Malang who do not have a personal vehicle, useful for vacations, homecoming, or trips to the airport.
Mahendra, Yusril Mauluddin
core
Evaluation of an anthropomorphic user interface in a travel reservation context and affordances [PDF]
, 2011 This paper describes an experiment and its results concerning research that has been going on for a number ofyears in the area of anthropomorphic user interface feedback.
Gee, A, Holt, PO, Murano, P
core