Results 91 to 100 of about 662,603 (329)
The functional reception interfaces and their aesthetic effectiveness in smart children's products
الاكاديميThis research addresses the aesthetic study of smart children's product interfaces and their effective use. It is considered one of the modern innovations in the field of product design aimed at this demographic.
Raneen Mohammed Hussein +1 more
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Designing Universal User Interfaces Through an Ontology-Based Method.
Revista Tecnologia, 2009 In recenty ears, universal access has attracted considerable attention by the research communities, mainly from the perspective of system development. It comes from the fact that the design of user interfaces for all must cover design issues in multiple ...
Elizabeth Furtado, Jean Vanderdonckt
doaj
A Comparison of One- and Two-Handed Gesture User Interfaces in Virtual Reality—A Task-Based Approach
Multimodal Technologies and InteractionThis paper presents two gesture-based user interfaces which were designed for a 3D design review in virtual reality (VR) with inspiration drawn from the shipbuilding industry’s need to streamline and make their processes more sustainable.
Taneli Nyyssönen +3 more
doaj +1 more source
Computer Programs, User Interfaces, and Section 102(b) of the Copyright Act of 1976: A Critique of Lotus v. Paperback [PDF]
, 1992 The Supreme Court\u27s landmark ruling Lotus Development Corp vs Paperback Software International is critiqued.
Samuelson, Pamela
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Target Acquisition in Multiscale Electronic Worlds [PDF]
, 2004 Since the advent of graphical user interfaces, electronic information has grown exponentially, whereas the size of screen displays has stayed almost the same.
Beaudouin-Lafon, Michel, Guiard, Yves
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source