Results 71 to 80 of about 5,614,936 (322)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Context-Aware Online Adaptation of Mixed Reality Interfaces
ACM Symposium on User Interface Software and Technology, 2019 We present an optimization-based approach for Mixed Reality (MR) systems to automatically control when and where applications are shown, and how much information they display.
David Lindlbauer +2 more
semanticscholar +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A decision support environment for behavioral synthesis [PDF]
, 1991 We present a specification of a general environment for behavioral synthesis centered around the user/designer as the primary motivator for decisions in design development.
Gajski, Daniel D., Hadley, Tedd
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Choosing a Color model in CBIR-Systems
Knjižnica, 2014 In the paper we study how the choice of color space affects the user-friendliness of the graphical user interface of CBIR. The pilot study was carried out on 46 students of the Department of Library and Information Science and Book Studies at the Faculty
Andrej Cimerman, Jasna Maver
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
ACM Symposium on User Interface Software and Technology, 2012 Malleable and organic user interfaces have the potential to enable radically new forms of interactions and expressiveness through flexible, free-form and computationally controlled shapes and displays.
Sean Follmer +4 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Culture and E-Learning: Automatic Detection of a Users’ Culture from Survey Data [PDF]
, 2005 Knowledge about the culture of a user is especially important for the design of e-learning applications. In the experiment reported here, questionnaire data was used to build machine learning models to automatically predict the culture of a user.
Kamentz, Elisabeth, Mandl, thomas
core