Results 131 to 140 of about 146,314 (303)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The Routledge Handbook of Service User Involvement in Human Services Research and Education [PDF]

This is an Accepted Manuscript of a book chapter published by Routledge in [The Routledge Handbook of Service User Involvement in Human Services Research and Education] on [11/08/2020], available online: http://www.routledge.com/The-Routledge-Handbook-of-
Gillian, Buck, Harriott, Paula, Tomczak, Philippa, Ryan, Kemi, Ryan, Natasha   +4 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Healthcare managers’ experiences of opportunities for user involvement in municipal health and care services

Nordisk Välfärdsforskning
In the Nordic welfare state, user involvement is a fundamental political and population right that healthcare managers must adhere to. Thus, the aim of this study is to investigate what opportunities healthcare managers in a small municipality in Norway ...
Erna Henriette Dahl Tyskø, Sari Lindeman, Lennart Lorås   +2 more
doaj   +1 more source

User involvement and value co-creation in well-being ecosystems. [PDF]

J Health Organ Manag, 2023
Poblete L, Eriksson E, Hellström A, Glennon R.   +3 more
europepmc   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Involvement of the end user: exploration of older people's needs and preferences for a wearable fall detection device – a qualitative descriptive study

Patient Preference and Adherence, 2016
Friederike JS Thilo,1,2 Selina Bilger,1 Ruud JG Halfens,2 Jos MGA Schols,2,3 Sabine Hahn1 1Applied Research and Development in Nursing, Health Division, Bern University of Applied Sciences, Bern, Switzerland; 2Department of Health Services Research ...
Thilo FJS, Bilger S, Halfens RJG, Schols JMGA, Hahn S   +4 more
doaj  

A Market of Lived Experience-User Involvement and the Commodification of Personal Experiences of Mental Illness. [PDF]

Int J Environ Res Public Health, 2023
Eriksson E.
europepmc   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source