Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Social exclusion and transport policy [PDF]
, 2004 This paper is a review of social inclusion in the specification by central government of policy instruments for local government. It forms part of the scooping study on Accessibility and User Needs in Transport (AUNT) funded by the EPSRC Sustainable ...
Titheridge, H.
core
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Needs-Led Research: A Way of Employing User Involvement in Establishing Research Questions on the Trust Model Within Community Home-Based Health Care Services in Norway [PDF]
, 2020 Ruth-Ellen Slåtsveen +3 more
openalex +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
User needs and design features of sanitation digital solutions in Kawempe division, Kampala Uganda: a user centered design approach. [PDF]
Front Public Health, 2023 Mukasa CH +4 more
europepmc +1 more source
A feasibility study: California Department of Forestry and Fire Protection utilization of infrared technologies for wildland fire suppression and management [PDF]
NASA's JPL has completed a feasibility study using infrared technologies for wildland fire suppression and management. The study surveyed user needs, examined available technologies, matched the user needs with technologies, and defined an integrated ...
Britten, R. A. +3 more
core +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source