Results 191 to 200 of about 2,245,729 (347)

Making mobility hubs more inclusive: what are the needs of vulnerable users?

, 2023
Lluis Martinez, Jesse Pappers, Imre Keserü   +2 more
openalex   +1 more source

French users need European neutrons [PDF]

Nature, 2002
F, Leclercq, H, Mutka
openaire   +2 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Ambivalent User Needs as a Challenge and Chance for the Design of a Web-Based Intervention for Gaming Disorder: Qualitative Interview Study With Adolescents and Young Adults. [PDF]

JMIR Form Res
Geisler BL, Petersen KU, Hanke S, Schurer S, Schreiber A, Lämmle C, Batra A, Renner T, Brandhorst I.   +8 more
europepmc   +1 more source

Assessing Clinical Software User Needs for Improved Clinical Decision Support Tools

, 2015
Kimberly B. Denney
openalex   +1 more source

User needs analysis and development of priorities for life cycle impact assessment

, 2004
Mary Stewart, Olivier Jolliet
openalex   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Enhancing prehospital decision-making: exploring user needs and design considerations for clinical decision support systems. [PDF]

BMC Med Inform Decis Mak
Bai E, Zhang Z, Xu Y, Luo X, Adelgais K.
europepmc   +1 more source

Satisfying heterogeneous user needs via innovation toolkits: the case of Apache security software

, 2003
Nikolaus Franke, Eric von Hippel
openalex   +2 more sources