Results 101 to 110 of about 990,969 (305)

Regression and Learning to Rank Aggregation for User Engagement Evaluation

open access: yes, 2014
User engagement refers to the amount of interaction an instance (e.g., tweet, news, and forum post) achieves. Ranking the items in social media websites based on the amount of user participation in them, can be used in different applications, such as ...
Moradi, Pooya   +2 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Balanced Objective-Quantifiers Method (BOQM) For Software Intensive Organizations Strategies [PDF]

open access: yes, 2008
Spanish university facilitates a method to link the strategic management with Software and Process improvement based on measurement. The method uses the process philosophy to build measurable information in Indicators templates (Based on ISO/IEC 15939 ...
De-Amescua Seco, Antonio
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Effect of an institutional development plan for user participation on professionals' knowledge, practice, and attitudes. A controlled study

open access: yesBMC Health Services Research, 2011
Background Governments in several countries attempt to strengthen user participation through instructing health care organisations to plan and implement activities such as user representation in administrational boards, improved information to users, and
Rise Marit By   +3 more
doaj   +1 more source

Decentralizing water resource management : economic incentives, accountability, and assurance [PDF]

open access: yes
Private sector involvement and user participation in water resource management are not new, say the authors. They give examples that demonstrate how willing users and the private sector are able to improve water use and play a larger role in water ...
DEC   +2 more
core  

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