Results 81 to 90 of about 185,131 (308)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

A goals/questions/metrics plan for monitoring user involvement and participation in ERP (...) [PDF]

ERP implementation success is influenced by a large number of factors. User involvement and participation is one of the most cited critical success factors in ERP implementation projects, and one of the most critical ones for their satisfactory outcome ...
JOSE MANUEL ESTEVES
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

An investigation of end user development success [PDF]

, 2002
User development of applications provides end users with an alternative to the traditional process of systems development by allowing them to solve job related problems by developing their own software applications.
McGill, Tanya Jane
core   +1 more source

The illness management and recovery program: a contribution to recovery-oriented secondary mental health services

BMC Health Services Research
Background In recent decades, mental health services have been challenged to offer evidence-based practices (EBPs) that are person-centered, human rights- and recovery-oriented.
Kristin B. Ørjasæter, Tone Winnem, Kristin Heiervang, Ottar Ness, Kim T. Mueser   +4 more
doaj   +1 more source

The Impact of User Participation Methods on E-Government Projects: The Case of La Louvière, Belgium

Media and Communication, 2018
In recent years, information and communication technologies (ICT) have allowed governments to improve their internal functioning and to improve the delivery of information and services to their users.
Anthony Simonofski, Benoît Vanderose, Antoine Clarinval, Monique Snoeck   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Hvordan praktisere brukermedvirkning uten brukeren?

Tidsskrift for velferdsforskning, 2018
Brukermedvirkning i behandling er en lovfestet rett i Norge. Hvordan er helsepolitiske føringer implementert i praksis? Vi diskuterte medvirkning med brukere, pårørende og tjenesteytere i rus og psykisk helsevern i en norsk kommune og ...
Guro Huby, Lasse Johnsen, Line Eikenes Langsholt, Mona Klubben   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

OPAC vs. card catalogue: a comparative study of user behaviour [PDF]

, 2004
Even though use studies of card catalogue are quite rare, use of OPAC has been extensively investigated since early 1980s. Yet there are not many attempts to conduct comparative studies highlighting the differences in use of card catalogue and OPAC of ...
M.S. Sridhar, Sridhar, M. S.
core   +1 more source