Results 61 to 70 of about 185,131 (308)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

A mechanism for activating end-user learning and participation in office automation [PDF]

open access: yes, 1990
This thesis is about 'User Involvement', a theme that is becoming the core of a growing body of research in the area of systems development and implementation.
Kaddah, Mona Maamoun, Kaddah, M.M
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The User : Silophone [PDF]

open access: yes, 2002
This publication documents the public audio art installation conceived by [The User] ( T. McIntosh and E. Madan) for the abandoned grain silo at the Old Port in Montreal.

core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

System quality, user satisfaction and end user development [PDF]

open access: yes, 1999
Organisations rely heavily on user developed applications (UDAs) to support organisational decision making, but for the most part the satisfaction of the user developer is the sole indicator of application success.
Payne, C.   +6 more
core   +1 more source

User councils for disabled people in Norway – from reactive to proactive?

open access: yesScandinavian Journal of Disability Research, 2015
User councils act as advisory bodies for the agencies with which they are associated. This article is based on interviews with user participants and agency representatives from a sample of user councils in Norway.
Jan Andersen
doaj   +1 more source

Predicting User Participation in Social Media

open access: yes, 2016
Online social networking services like Facebook provides a popular way for users to participate in different communication groups and discuss relevant topics with each other. While users tend to have an impact on each other, it is important to better understand and analyze users behavior in specific online groups.
Fredrik Erlandsson   +3 more
openaire   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

User involvement in health and social care education: A concept analysis [PDF]

open access: yes, 2012
This paper presents an evaluative discussion of the literature, and findings from a concept analysis which explores user involvement in the context of health and social care higher education in the United Kingdom.
Rhodes, Christine A.   +2 more
core   +1 more source

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