Results 161 to 170 of about 990,969 (305)
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
An mHealth Application in German Health Care System: Importance of User Participation in the Development Process. [PDF]
J Med SystBickmann P, Froböse I, Grieben C.
europepmc +1 more source
Research with and about user participation: potentials and challenges. [PDF]
Aging Clin Exp Res, 2018 Kylberg M, Haak M, Iwarsson S.
europepmc +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
User participation and mental health
, 2005 Download for free Rapporten er første fase i et prosjekt som undersøker brukeres og pårørendes erfaringer med medvirkning og samordning i psykiatrien. Erfaringene blant brukerne varierer sterkt, men brukerne ønsker generelt sterkere innflytelse på egen behandling. Det oppleves at ingen i behandlingsapparatet tar ansvar for brukerne, og at brukere selv
Sidsel Sverdrup +2 more
openaire
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
A Study Protocol for Applying User Participation and Co-Learning-Lessons Learned from the eBalance Project. [PDF]
Int J Environ Res Public Health, 2017 Åberg AC +5 more
europepmc +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source