Results 21 to 30 of about 2,697,086 (242)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

System quality, user satisfaction and end user development [PDF]

open access: yes, 1999
Organisations rely heavily on user developed applications (UDAs) to support organisational decision making, but for the most part the satisfaction of the user developer is the sole indicator of application success.
Payne, C.   +6 more
core  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

2012 XSEDE User Satisfaction Survey [PDF]

open access: yes, 2016
This is the final report from the 2012 XSEDE User Satisfaction Survey.National Science Foundation OCI ...

core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

The Effect Of The Information System Quality, Service Quality, And User Satisfaction On Academic Information System User Loyalty [PDF]

open access: yes, 2021
The purpose of the study is to analyze the effect of the information system quality, service quality and user satisfaction on user loyalty. Primary data obtained by questionaires are the main data in this analisys.
Kurniawan, Irham   +2 more
core   +1 more source

Sure Start Widnes Trailblazer user satisfaction survey [PDF]

open access: yes, 2005
This project report discusses a user satisifaction survey with Sure Start services in the WidnesTrailblazer area.The project report was commissioned by Sure Start Widnes Trialblazer and funded by Halton Brough ...
Alford, Simon, Perry, Catherine
core   +2 more sources

User Satisfaction Analysis of the Muslim Pro Application using PIECES Method

open access: yesSistemasi: Jurnal Sistem Informasi
User satisfaction serves as a benchmark for applications and helps developers improve the quality of future applications. Muslim Pro is an application that provides various services for Muslims.
sri anjani   +3 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

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