Results 41 to 50 of about 94,789 (264)

Individual Persistence Adaptation for User-Centric Evaluation of User Satisfaction in Recommender Systems

open access: yesIEEE Access
The primary objective of a recommender system (RS) is to enhance user satisfaction, which serves as the gold standard for evaluation. In order to support the advancement of RS, it is crucial to study how to accurately measure user satisfaction.
Nozomu Onodera   +3 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Analisis Pengaruh Kualitas Website Shopee Terhadap Kepuasan Pengguna Berdasarkan Metode WebQual 4.0 (Studi Kasus : Mahasiswa Pengguna Shopee di Universitas Diponegoro)

open access: yesJurnal Masyarakat Informatika
Maraknya pelaku bisnis e-commerce membuat persaingan jual beli online menjadi ketat sehingga e-commerce harus mampu mempertahankan keberadaannya. Salah satu faktor utama yang mendorong pelanggan melakukan kegiatan e-commerce adalah tingkat kepuasan ...
M. Risqi Amirul Adieb   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

User Satisfaction Using Webqual Instrument: A Research on Stock Exchange of Thailand (SET)

open access: yesJurnal Akuntansi dan Keuangan, 2008
User satisfaction held an important position in an organization to measure information system implementation excellence. Therefore, it is necessary for an organization to evaluate their delivered service using end-user satisfaction as feedback.
Josua Tarigan
doaj  

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

open access: yes
Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein   +11 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

PENERAPAN MODEL DELONE DAN MCLEAN PADA SI-PMB ONLINE DARI PERSPEKTIF PENGGUNA UNTUK MENINGKATKAN KUALITAS LAYANAN

open access: yesSimetris: Jurnal Teknik Mesin, Elektro dan Ilmu Komputer, 2020
Inovasi strategi pengembangan sistem informasi perlu dikembangkan untuk mendukung kesuksesan dan kualitas layanan sistem penerimaan mahasiswa baru. Masyarakat pengguna sistem informasi penerimaan mahasiswa baru sering mengalami kesulitan ketika mencari ...
Agustinus Suradi   +1 more
doaj   +1 more source

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