Results 111 to 120 of about 14,502,433 (244)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Exploring LLM-powered multi-session human-robot interactions with university students

Frontiers in Robotics and AI
This exploratory study investigates how open-domain, multi-session interactions with a large language model (LLM)-powered social humanoid robot (SHR), EMAH, affect user perceptions and willingness for adoption in a university setting.
Mauliana Mauliana, Ashita Ashok, Daniela Czernochowski, Karsten Berns   +3 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Emu: Engagement Modeling for User Studies. [PDF]

Proc ACM Int Conf Ubiquitous Comput, 2017
Ho BJ, Nikzad N, Balaji B, Srivastava M.
europepmc   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

BC Studies 2017 conference poster

, 2016
Poster for (Un)setting British Columbia - BC Studies 2017 conference. Conference date: May 4 - 6, 2017.
BC Studies
core  

System quality, user satisfaction and end user development [PDF]

, 1999
Organisations rely heavily on user developed applications (UDAs) to support organisational decision making, but for the most part the satisfaction of the user developer is the sole indicator of application success.
Payne, C., Lim, L, McGill, T.J., Bennett, D., Carter, K., Chong, A., Hornby, G.   +6 more
core  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

A Concept for Conducting User Studies in Vehicles and Stationary Test Rooms During the COVID-19 Pandemic

, 2021
Kantusch T, Sinanovic A, Marker S.
europepmc   +1 more source