Results 171 to 180 of about 45,455,378 (308)
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Exploring the Role of App Features in Providing Continuity of Care to Users on a Digital Mental Health Platform (Wysa): Retrospective Mixed Methods Observational Study. [PDF]
Sinha C, Thakkar R, Meheli S, Dinesh D.
europepmc +1 more source
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
From fees to free: impacts of user fee removal on child health outcomes - a systematic review. [PDF]
Dehnavi H +3 more
europepmc +1 more source
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
From abandonment to adoption: advancing assistive technologies for blindness and low vision in the AI era. [PDF]
Barak Ventura R +2 more
europepmc +1 more source
Supplementary material for the paper “LLM-Assisted Optimization of Waiting Time in Business Processes: A Prompting Method” by K. Lashkevich et al. submitted to BPM'24.
openaire +1 more source

