Results 231 to 240 of about 2,837,339 (265)

Adoption, usage patterns, and perceptions of DeepSeek among medical interns: Evidence from a Chinese Teaching Hospital. [PDF]

PLoS One
Zhang T, Pan D, Zhang Z, Zhang X, Wang M.   +4 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Investigating GLP-1 sourcing preferences on social media and motivations for use: Survey with choice-based conjoint (CBC) exercise. [PDF]

PLoS One
Haupt MR, Weiss SM, Calac AJ, Salazar S, Larsen MZ, Mackey TK.   +5 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Secondary School Staff Engagement With a School-Based Physical Activity and Sedentary Behavior Initiative Website: Implementation Trial During National Scale-Up. [PDF]

JMIR Form Res
Fitriani A, Contardo Ayala AM, Koorts H, Lai SK, Salmon J.   +4 more
europepmc   +1 more source

Development process and user experiences of an online support program for first-time hearing aid users. [PDF]

Front Digit Health
Ahlberg S, Ivarsson L, Brännström KJ, Öberg M, Thorén ES.   +4 more
europepmc   +1 more source

Sycophancy and Extended Engagement with Publicly Accessible Generative AI: Aligning Deployment with Mental Health Needs. [PDF]

Curr Psychiatry Rep
Hopkins AM, Modi ND, Rowland A, Schultz TJ, Gradon KT, Battersby MW, Menz BD.   +6 more
europepmc   +1 more source