Results 171 to 180 of about 2,734,396 (306)

Engaging Service Users in Co-Designing a Nurse-Led Weight Talk Tool for Low- and Medium-Secure Mental Health Inpatient Settings: A Participatory Intervention Development Study. [PDF]

Int J Ment Health Nurs
Mak NKN, Dibb B, Stokes N, Barley EEA, Zasada M.   +4 more
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Design Guidelines for Online Health Forums: User-Centered Design Approach. [PDF]

J Med Internet Res
Marshall P, Caton N, Lindroos Cermakova A, Dock B, Glossop Z, Jones S, Haines J, Lodge C, Machin K, Rycroft-Malone J, Meacock R, Peters D, Rayson P, Robinson H, Salhi L, Staff J, Lobban F.   +16 more
europepmc   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Response of RC slab strips subjected to axial tension and transverse load

, 2014
BELLETTI, Beatrice, DAMONI, Cecilia, Hendriks, M. A. N.   +2 more
core  

Evaluation of the Finnish Exposure Notification App "Koronavilkku" According to Key Performance Indicators: Cross-Sectional Study. [PDF]

JMIR Public Health Surveill
Kitowska W, Pihlajamäki M, Wickström S, Tolmunen K, Helve O, Mykkänen J, Dub T, Siira L.   +7 more
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Family-centred psycho-oncological counselling for parents with cancer: a longitudinal secondary data analysis of psychological distress, family functioning and parental concerns. [PDF]

BMC Cancer
Geertz W, Inhestern L, Scholl I, Bergelt C.   +3 more
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Assessing the use of the input of care users in long-term care homes during 2020-2023 in the Netherlands: an exploratory study. [PDF]

BMJ Open Qual
Palimetaki F, Schouteten R.
europepmc   +1 more source