Results 111 to 120 of about 32,890 (266)
Profile of tildrakizumab-asmn in the treatment of moderate-to-severe plaque psoriasis: evidence to date. [PDF]
, 2018 Plaque psoriasis is an immune-mediated skin disease that affects roughly 3% of adults in the United States. Advances over the past 20 years in understanding the immune-mediated pathophysiology of psoriasis have led to the development of targeted biologic
Beck, Kristen M +3 more
core
Emerging Therapies for the Treatment of Psoriasis [PDF]
, 2012 Psoriasis is an immune-mediated disease that affects 1%–2% of the European and North American population. While topical agents such as corticosteroids and vitamin D derivatives are prescribed for mild disease, they are generally unable to adequately ...
Alan Menter +3 more
core +1 more source
Laser therapy in superficial morphea lesions – indications, limitations and therapeutic alternatives [PDF]
, 2020 Morphea or localized scleroderma is an uncommon autoimmune and inflammatory disease which affects patients of any age. Even if morphea lesions present systemic symptoms as myalgias or arthritis, it is distinct from systemic sclerosis because it does not ...
Ardeleanu, Valeriu +4 more
core +2 more sources
Observational study of metastatic vulvar Crohn's disease in the pediatric population
JPGN Reports, EarlyView.Abstract Objective Metastatic vulvar Crohn's disease (MVCD) is a rare cutaneous manifestation of Crohn's disease (CD), especially in pediatric patients. The objective of this study is to assess presentation, diagnosis, and treatment for pediatric MVCD in the largest cohort reported. Methods This is a retrospective review of pediatric patients with MVCD
Deborah Winograd +6 more
wiley +1 more source
Drugs in R&DBackground SB17 is being developed as a biosimilar to ustekinumab reference product (RP), a human monoclonal antibody (IgG1 kappa immunoglobulin) that binds to the common p40 subunit of cytokines interleukin (IL)-23 and IL-12.
Sung-Yong Yang +6 more
doaj +1 more source
Lessons from helminth infections: ES-62 highlights new interventional approaches in rheumatoid arthritis [PDF]
, 2014 Parasitic worms are able to survive in their mammalian host for many years due to their ability to manipulate the immune response by secreting immunomodulatory products. It is increasingly clear that, reflecting the anti-inflammatory actions of such worm-
Al-Riyami, L. +3 more
core +1 more source
Efficacy of upadacitinib induction for pediatric inflammatory bowel disease
JPGN Reports, EarlyView.Abstract Objectives Upadacitinib, a second‐generation Janus kinase (JAK) inhibitor, is approved for moderate to severe Crohn's disease (CD) and ulcerative colitis (UC) in adults. Its efficacy in pediatric patients remains unclear, though early reports suggest benefits in refractory inflammatory bowel disease (IBD).
Evan Greenhall +5 more
wiley +1 more source
Current Therapeutic Research: Ustekinumab is a first-line drug for Crohn's disease. However, little is known about its potential adverse effects on renal function. We present the case of a 42-year-old man with Crohn's disease who developed chronic renal dysfunction during ...
Yuge Wei, Ms +4 more
doaj +1 more source
Successful treatment of hidradenitis suppurativa in the setting of Crohn disease with combination adalimumab and ustekinumab [PDF]
, 2019 Herein we report the combination of adalimumab and ustekinumab to successfully treat a 39-year-old woman who presented for evaluation of hidradenitis suppurativa in the setting of Crohn disease of both the small and large intestine.
Cline, Abigail, Pichardo, Rita O
core
A Review of Biologic Therapies Targeting IL-23 and IL-17 for Use in Moderate-to-Severe Plaque Psoriasis [PDF]
, 2007 International audienceThis paper presents numerical crack propagations in case of explicit dynamics, and applied to eXtended Finite Element Method. The interest of this method is non remeshing. Hence the crack propagates through the constant mesh.
Campa, Molly +3 more
core +1 more source