Results 51 to 60 of about 493,726 (266)

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

Advanced Healthcare Materials, EarlyView.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull, Mingxin Shi, Madeleine E. Harvey, Taylor M. Page, Rishi Sharma, Kenneth John Goody, Aqib Iqbal Dar, Nash S. Moawad, Vijay Kumar Sirohi, Paul S. Cooke, Kanako Hayashi, Anjali Sharma   +11 more
wiley   +1 more source

Uterine and umbilical artery doppler in women with pre-eclampsia and their pregnancy outcomes

Nigerian Postgraduate Medical Journal, 2019
Background: Pre-eclampsia (PE) is an important public health menace in both developed and developing countries with high maternal and perinatal morbidity and mortality globally.
Ademola Joseph Adekanmi, Adebola Roberts, Janet Adetinuke Akinmoladun, Abiodun Oludotun Adeyinka   +3 more
doaj   +1 more source

Uterine Leiomyoma with Massive Lymphoid Infiltrate in a Patient with History of Assisted In-Vitro Fertilization

Türk Patoloji Dergisi, 2020
Uterine leiomyomas are the most common benign tumors of the gynecological tract. Massive lymphocytic infiltration has been reported rarely in uterine leiomyomas and it has been described as a pathogenetic correlation with gonadotropin-releasing hormone ...
Monia DI PRETE, Matteo COLLAMARINI, Claudio COLLAMARINI, Francesco SESTI, Alessandro MAURIELLO, Giampiero PALMIERI   +5 more
doaj   +1 more source

Increased angiogenic factor secretion by decidual natural killer cells from pregnancies with high uterine artery resistance alters trophoblast function. [PDF]

, 2014
STUDY QUESTION Are the concentrations of factors secreted by decidual natural killer (dNK) cells from pregnancies at high risk of poor spiral artery remodelling different to those secreted from pregnancies at low risk?
Whitley, G S, Goulwara, S S, Johnstone, A P, Cartwright, JE, Whitley, GS, Goulwara, SS, Cartwright, J E, Wallace, A E, Fraser, R, Gurung, S, Wallace, AE, Johnstone, AP   +11 more
core   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Prompt Diagnosis and Treatment of Uterine Arcuate Artery Pseudoaneurysm: A Case Report and Review of Literature [PDF]

Journal of Clinical and Diagnostic Research, 2013
Post–partum haemorrhage is a major determinant of maternal mortality. Traditionally, cases of post–partum haemorrhage caused by arterial injuries were managed by caesarean hysterectomies or bilateral internal iliac artery ligations.
Nidhi Sharma, Deepa Ganesh, Lakshmi Devi, Jayashree Srinivasan, Upasana Ranga   +4 more
doaj   +1 more source

Uterine angioleiomyoma – a rare variant of uterine leiomyoma: review of literature and case reports

, 2016
Introduction: Uterine angioleiomyoma (AL) is an extremely rare variant of uterine leiomyoma. It is composed of smooth muscle cells and thick-walled blood vessels. Angioleiomyoma usually occurs in middle-aged women, 40-60 years old. Aim of the study was
Dobrosława L. Sikora-Szczęśniak
core   +1 more source

Kv7 and Kv11 channels in myometrial regulation. [PDF]

, 2013
Ion channels play a key role in defining myometrial contractility. Modulation of ion channel populations is proposed to underpin gestational changes in uterine contractility associated with the transition from uterine quiescence to active labour.
Tribe, Rachel M; id_orcid, Greenwood, IA, Rachel M. Tribe, Greenwood, Iain, Iain A. Greenwood, Tribe, RM   +5 more
core   +1 more source

Uterine Transplant: A New Option to Restore Fertility [PDF]

, 2023
The uterine transplant has been thought of as a treatment for women with absolute uterine factor infertility, allowing them to procreate, carry a pregnancy and give birth to genetic children not intended for lifelong use.
Claudia MEHEDINTU, Monica CIRSTOIU, Roxana Georgiana BORS, Valentin VARLAS   +3 more
core   +2 more sources

Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis

Advanced Science, EarlyView.
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa, Silke De Vriendt, Lixian Liu, Thalles Fernando Rocha Ruiz, Hugo Vankelecom, Christiani Andrade Amorim   +5 more
wiley   +1 more source